Authors

Can You Collect Disability Benefits For Burnout?

Physician's applying for disability due to "burnout" need to be prepared to combat insurance companies seeking to trivialize and downplay the situation.

Medication adherence and meaningful clinical markers in diabetes mellitus

Diabetes mellitus is a chronic disease for which nonadherence to therapy is frequent.

Impaired coronary blood flow reserve in prehypertension and function

Despite the fact that prehypertension has been shown to be associated with atherosclerosis and target-organ damage, no studies evaluating coronary flow reserve (CFR) among prehypertensive patients have been done. We assessed CFR in normotensive subjects, in subjects with prehypertension, and in newly diagnosed and never-treated subjects with established hypertension. We found that CFR was decreased in prehypertensive subjects, although not as significantly as in subjects with hypertension.

Phase III Extended Trial Finds Pixantrone Favorable Compared with Commonly Used Chemotherapies in Aggressive NHL

Single-agent pixantrone, an investigational agent, showed encouraging third-line responses, duration of responses, and progression-free survival (PFS) compared with other single-agent chemotherapies in patients with relapsed aggressive non-Hodgkin lymphoma (NHL) in the phase III, randomized, open-label, multicenter EXTEND trial. In the study, patients with relapsed/refractory NHL treated with pixantrone achieved significant increases in complete response (CR) and overall response (ORR) and demonstrated a positive trend in overall survival (OS) compared with other chemotherapy agents, according to Ruth Pettengell, MD, of St. Georges Hospital in London, who presented these results at a poster session. “An anthracycline with reduced cardiotoxicity that can be used for salvage therapy of aggressive NHL meets a significant unmet medical need,” she said.

Dronedarone: Boon or bust?

Atrial fibrillation affects over 2.2 million Americans and is estimated to affect up to 10 million by 2050.

Angle for Some Fishing Opportunities

2011 AAN Pre-conference Coverage: Non-Alzheimer's Dementia

When a dementia diagnosis isn't Alzheimer's diease, the neurologist's job becomes much trickier.

Patent foramen ovale closure for stroke prevention: A myriad of unanswered questions

Migraines, including those with aura, are common and generally benign, affecting between 10% and 15% of the population.

Assemble a Team that Succeeds for You

Interventional Pain Management: Let's Abandon the Safe Triangle

Using the widely taught 'safe triangle' approach to transforaminal epidural injections can paralyze patients. There's a safer way.

Comprehensive lifestyle modification and blood pressure control

Lifestyle recommendations for the prevention and treatment of hypertension include weight loss, reduced sodium intake, increased physical activity, limited alcohol intake, and the Dietary Approaches to Stop Hypertension (DASH) diet. The 18-month results of the Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER) randomized clinical trial showed that individuals with prehypertension and stage 1 hypertension can make and sustain many of these lifestyle changes over the long term, thereby reducing their risk of cardiovascular disease.