Advances in Treatment of Obstructive Hypertrophic Cardiomyopathy

EP. 1: Overview of Hypertrophic Cardiomyopathy
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Martin S. Maron, MD, discusses the incidence and prevalence of hypertrophic cardiomyopathy and age of disease expression.

EP. 2: Role of Genetic Mutations in HCM Pathophysiology
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Steve R. Ommen, MD, leads a review of common mutations seen in hypertrophic cardiomyopathy and the role of biomarkers and genetic testing in HCM.

EP. 3: Symptoms of Hypertrophic Cardiomyopathy
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Drs Steve R. Ommen, Martin S. Maron, John A. Spertus, Javed Butler, and James Januzzi provide insight on the presentation of nonobstructive and obstructive hypertrophic cardiomyopathy.

EP. 4: The Effect of Obstructive Hypertrophic Cardiomyopathy on Health Status
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA John A. Spertus, MD, MPH, comments on the effect of oHCM on health status and quality of life for patients.

EP. 5: AHA/ACC HCM Guidelines and Patient Identification and Management
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Steve R. Ommen, MD; and Martin S. Maron, MD, review the role of AHA/ACC guidelines, imaging techniques, and circulating biomarkers in approaching the diagnosis and treatment of hypertrophic cardiomyopathy.

EP. 6: Treatment Approaches for HCM
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Drs Javed Butler, Martin S. Maron, Steve R. Ommen, and James Januzzi provide insight on approaching treatment of HCM with pharmacologic and nonpharmacologic interventions.

EP. 7: Invasive Treatments and Challenges with HCM Treatments
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Experts in cardiology review invasive treatments, challenges with HCM treatments, and how to optimize treatment for patients.

EP. 8: Approaching Treatment Selection for Hypertrophic Cardiomyopathy
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Steve R. Ommen, MD, leads a discussion on factors to consider when choosing treatment for hypertrophic cardiomyopathy (HCM).

EP. 9: Emerging Therapies for oHCM
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Steve R. Ommen, MD, discusses the use of novel agents in the pipeline for the treatment of obstructive hypertrophic cardiomyopathy (oHCM).

EP. 10: EXPLORER-HCM Trial in oHCM
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA John A. Spertus, MD, MPH, and Martin S. Maron, MD comment on the role of mavacamten in oHCM as seen in the EXPLORER-HCM trial.

EP. 11: Health Status With Different HCM Treatments
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Cardiac specialists discuss improvement in health status with different treatments for hypertrophic cardiomyopathy.

EP. 12: Long-Term Data of Mavacamten Use in oHCM
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Martin S. Maron, MD, examines long-term data with mavacamten for oHCM treatment that was presented at ACC 2022.

EP. 13: VALOR-HCM Study in oHCM
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA A panel of experts in cardiovascular medicine review the use of mavacamten as seen in the VALOR-HCM study for patients with symptomatic oHCM who are eligible for septal reduction therapy.

EP. 14: Future Directions for oHCM Treatment
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Drs Steve R. Ommen, Martin S. Maron, Javed Butler, and James Januzzi provide insight on the evolving treatment landscape for obstructive hypertrophic cardiomyopathy.

EP. 15: Patient Education of HCM
ByJames Januzzi, MD,Steve R. Ommen, MD,John A. Spertus, MD, MPH,Martin S. Maron, MD,Javed Butler, MD, MPH, MBA Expert cardiologists share strategies for educating patients on the treatment and management of hypertrophic cardiomyopathy.