
Intermediate- and high-risk status signals a struggling right ventricle and a prognosis the panel considers unacceptable. They argue for treating risk assessment as a routine vital sign while weighing what patients say they want from therapy.
Pulmonary hypertension experts discuss individualizing therapy for pulmonary arterial hypertension (PAH), from guideline-based risk stratification and upfront combination therapy to escalation, switching, and parenteral transitions, with practical guidance on right heart assessment, adherence, emerging therapies, and partnering with community clinicians.

Intermediate- and high-risk status signals a struggling right ventricle and a prognosis the panel considers unacceptable. They argue for treating risk assessment as a routine vital sign while weighing what patients say they want from therapy.

PAH rarely belongs to a single specialty. The panel describes the team-based model behind effective care and reviews how four complementary treatment pathways now give clinicians a broad toolbox.