Navigating Hypoparathyroidism: Understanding the Multisystem Burden and Optimizing Patient Care
EP. 1: Hypoparathyroidism: Recognizing Signs, Symptoms, and Etiologies
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU Welcome back to another HCPLive Peer Exchange series. In this episode titled "Hypoparathyroidism: Recognizing Signs, Symptoms, and Etiologies," moderator Dr. Natalie Cusano discusses hypoparathyroidism with Dr. Sara Lubitz, Dr. Dolores Shoback, Dr. Andrea Ferenczi, and Dr. Azarmindokht Khosravi.
EP. 2: Diagnosing Hypoparathyroidism and Establishing a Multisystem Baseline
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Lubitz to walk through the diagnostic approach to hypoparathyroidism, followed by Dr. Khosravi on establishing a multisystem baseline after diagnosis.
EP. 3: Quality of Life in Hypoparathyroidism: Burden Across Four Domains
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Andrea Ferenczi to explain how hypoparathyroidism affects patients' quality of life and daily function, and whether the impact differs by etiology.
EP. 4: Neurologic, Neurocognitive, and Cardiovascular Complications of Hypoparathyroidism
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Dolores Shoback to elaborate on the neurologic and neurocognitive complications of hypoparathyroidism, and then asks Dr. Sara Lubitz to discuss the cardiovascular risks.
EP. 5: Musculoskeletal Complications of Hypoparathyroidism
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Azar Khosravi to discuss the musculoskeletal complications of hypoparathyroidism.
EP. 6: Renal Complications of Chronic Hypoparathyroidism
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Andrea Ferenczi to discuss the renal complications of chronic hypoparathyroidism.
EP. 7: Multisystem Monitoring and Coordination of Hypoparathyroidism Care
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Dolores Shoback how she prioritizes and coordinates multisystem monitoring across the full range of hypoparathyroidism complications in clinical practice.
EP. 8: Goals of Treatment and Special Considerations in Hypoparathyroidism
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Andrea Ferenczi to describe the goals of treatment in hypoparathyroidism and explain how management strategies differ by etiology, with particular attention to autosomal dominant hypocalcemia type 1 (ADH1).
EP. 9: Overview of the Hypoparathyroidism Treatment Landscape
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Khosravi to provide a comprehensive overview of the current treatment landscape for hypoparathyroidism, including both conventional therapy and novel options.
EP. 10: Limitations of Conventional Therapy and Transitioning to PTH Replacement in Hypoparathyroidism
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Andrea Ferenczi to elaborate on the limitations of conventional therapy, the monitoring approach over time, and the factors that guide a transition to PTH replacement.
EP. 11: Palopegteriparatide in Hypoparathyroidism: Mechanism, Long-Term Efficacy, and Clinical Experience
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Sara Lubitz to explain the mechanism of action and administration of palopegteriparatide, then turns to Dr. Dolores Shoback for a review of long-term clinical trial data and patient-reported outcomes.
EP. 12: Emerging Therapies in Hypoparathyroidism and Renal Outcomes of PTH Replacement
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Sara Lubitz to discuss eneboparatide, an emerging PTH-1 receptor agonist for hypoparathyroidism, and then asks Dr. Dolores Shoback to compare the renal outcomes seen across PTH replacement therapies in clinical trials.
EP. 13: Multisystem Complications: Guiding Treatment Selection in Hypoparathyroidism
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Khosravi to explain how multisystem complications beyond renal disease factor into treatment selection and monitoring in hypoparathyroidism.
EP. 14: Hypoparathyroidism Management During Pregnancy and Breastfeeding
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Sara Lubitz to address management of hypoparathyroidism in pregnant and postpartum patients.
EP. 15: Hypoparathyroidism in Special Populations: Pediatric, Geriatric, and Comorbid Patients
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Andrea Ferenczi to describe how hypoparathyroidism management must be adapted for special populations, including children, older adults, and those with significant comorbidities.
EP. 16: Unmet Needs in the Hypoparathyroidism Treatment Landscape
ByNatalie Cusano, MD, MS ,Sara Lubitz, MD,Azarmindokht Khosravi, MD,Dolores Shoback, MD,Andrea Ferenczi, MD, FACE, ECNU In this episode, Dr. Cusano asks Dr. Khosravi to identify the most significant unmet needs remaining in the current treatment landscape for hypoparathyroidism.
