
Opinion|Videos|August 7, 2024
Efficacy and Safety of Subcutaneous Infliximab
Author(s)Jean-Frederic Colombel, MD
A key opinion leader analyzes the clinical remission and endoscopic response data from the LIBERTY CD and LIBERTY UC trials for subcutaneous infliximab-dyyb injection, contrasts it with intravenous infliximab, and evaluates the drug's safety and efficacy profile.
Advertisement
- What are the key findings regarding the clinical remission and endoscopic response of subcutaneous infliximab-dyyb injection from the LIBERTY CD and LIBERTY UC trials?
- How does subcutaneous infliximab injection compare to IV infliximab in terms of sustenance of drug levels?
- Are there any clinical advantages of the subcutaneous delivery over the IV route?
- How does the safety profile of subcutaneous infliximab injection compare to IV infliximab?
Advertisement
Related to this article

End-of-study B-Well data show 91% of patients with chronic hepatitis B who achieved functional cure with bepirovirsen maintained it through Week 96.

With LDL-C target-guided titration, starting statin plus ezetimibe vs a statin alone yielded similar 3-year events in ASCVD.

Stopping statins was noninferior at 2 years in adults 70 and older without CVD, but events were higher over full follow-up (12.7% vs 9.2%).

Post hoc phase 2 data show survodutide improved MASH and fibrosis endpoints across all weight loss categories, including patients losing less than 5%.

Asundexian lowered ischemic stroke without more major bleeding across low, intermediate, and high Framingham risk groups (all P interaction > .25).

Adding spironolactone lowered 3-month home SBP by 7.7 mm Hg vs standard care in 160 stroke survivors with uncontrolled hypertension.

A systolic target below 120 mm Hg lowered major cardiovascular events vs below 140 mm Hg in 4368 patients with prior ischemic stroke or TIA.
Advertisement
Advertisement
Trending on HCPLive
1
Lp(a) HORIZON Shows Pelacarsen Lowers Lp(a) 78% But Not Cardiovascular Events
2
Cannabis Use Tied to Higher Odds of Stroke, Cardiovascular Disease
3
AHA 2026: Intensive Blood Pressure Control Reduces Events After Ischemic Stroke
4
STREAM: Statin Discontinuation Noninferior in Older Adults Without CVD
5

