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This Year In Medicine 2025

Opinion|Videos|July 20, 2023

Screening for Alzheimer Disease: Facilitating an Early Diagnosis for Prompt Intervention

Author(s)Marc Agronin, MD, Stephen Scheinthal, DO, DFACN, DFAPA, CS, Elaine Peskind, MD

In this episode of MEDcast, expert geriatric psychiatrists explore the urgent need for effective diagnostic methods that can detect Alzheimer’s disease at an early stage. We will discuss blood-based biomarkers and other advancements that can help screen Alzheimer’s disease non-invasively and early in the disease course.

Episodes in this series

EP. 1 Screening for Alzheimer Disease: Facilitating an Early Diagnosis for Prompt Intervention

EP. 1 Screening for Alzheimer Disease: Facilitating an Early Diagnosis for Prompt Intervention

EP. 2 Screening for Alzheimer’s Disease: Facilitating an Early Diagnosis for Prompt Intervention

EP. 2 Screening for Alzheimer’s Disease: Facilitating an Early Diagnosis for Prompt Intervention

0:00 Introduction

1:35 Importance of early diagnosis of Alzheimer’s disease

05:48 The pathophysiology of Alzheimer’s disease

09:32 Screening for Alzheimer’s disease

11:18 The role of biomarkers

13:15 Genetic testing

17:17 Ethics of genetic testing

17:54 The role of imaging

21:37 Utility and practicality of PET scans

24:00 CSF-based biomarkers

27:15 Promising blood-based biomarkers

30:48 Summary

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