Opinion|Videos|January 26, 2026

Key Symptoms of PBC- Fatigue, Pruritus, and Bone Health

Explore the complex relationship between pruritus, fatigue, and bone health in patients with primary biliary cholangitis (PBC).

In this episode, “Key Symptoms of PBC: Fatigue, Pruritus, and Bone Health,” the expert hepatologists explore extrahepatic symptoms associated with this disease.

Led by the moderator, the panelists examine the following critical questions:

What do we know about the underlying causes of these extrahepatic symptoms of primary biliary cholangitis?

Another common complication associated with PBC is bone disease; about 30% of patients with PBC also have osteoporosis. How often do you see bone complications in clinic, and how does it impact a patient’s quality of life?

Throughout the conversation, the experts provide a comprehensive reflection on the field and the factors that may shape how clinicians approach care moving forward.

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