Chelsie Derman

A new study revealed patients with genetic variation of hCAZyme enzymes were more likely to reach success with low-carb diets to relieve IBS symptoms than those without.

Brain-gut behavioral treatments, such as CBT and hypnotherapy, may alleviate abdominal pain in IBS, though no single therapy proves superior to others.

A study links hepatitis C infection and Parkinson's disease, identifying 19 genes with shared expression changes and highlighting sex-specific immune responses.

A study found that adding depression to Life's Essential 8 provides minimal improvements in predicting cardiovascular and all-cause mortality risk.

A new meta-analysis found elevated triglyceride levels in patients with major depressive disorder, potentially explaining the link between depression and cardiovascular risks.

A recent study demonstrated physicians surpass GPT-4- or GPT-3.5 turbo at making clinical recommendations in the emergency department.

A new study found that the more military personnel are exposed to open burn pits over time, the greater their odds will be for developing headache disorders or migraine.

A new prospective study discovered predictors for mortality among patients with sepsis admitted to the emergency department, including age, history of cancer, and dementia.

Following the approval of sodium oxybate for cataplexy in adults with cataplexy, the FDA approves this indication for the pediatric population.

A new study identifies antipsychotics to avoid for patients with schizophrenia who have cognitive deficits, including haloperidol, fluphenazine, and clozapine.

A study found infants under 1 year with food allergies can safely consume small doses of allergens, which helps reduce allergic reactions later in life.

A new study identified 9 distinct trajectories of asthma and allergy in children, with variations in disease progression, parental reporting, and medication use.

The study found that, following gradual policy changes, children with acute liver failure requiring a transplant now face a reduced risk of both mortality and graft failure from 1989.

A new study highlights suboptimal HDV screening rates in HBV-infected individuals, suggesting that treating HBV may improve survival for those with HDV coinfection.

A study found that migraine-related disability worsens health-related quality of life, with gender-specific differences, particularly affecting women with mild disability.

Phase 3 data found 66.5% of people with migraine attacks treated with STS101 had headache pain relief two hours after the dose.

A meta-analysis revealed taking pregabalin with supplement vitamin D reduced migraine frequency in children by 88%

A study finds CGRP monoclonal antibodies are not clinically superior to topiramate or Botox in treating chronic migraines, raising cost-effectiveness concerns.

Xanomeline trospium chloride offers a new pathway in schizophrenia treatment, improving cognitive symptoms without D2 receptor-related side effects like tardive dyskinesia.

HCPLive spoke with Monroe regarding muscarinic modulators, both the ones in development and xanomeline trospium chloride capsules (Cobenfy).

Comorbid migraine and insomnia are linked to altered locus coeruleus connectivity, suggesting it is a biomarker for sleep disturbances and a potential therapeutic target.

A meta-analysis shows that wet cupping reduces migraine intensity but doesn't improve quality of life. Adjunctive therapies offer limited additional benefits.

HCPLive spoke with Maguire about the benefits of acetylcholine and muscarinic receptors for the treatment of schizophrenia.

A recent study shows the FDA's black-box warnings on antidepressants have led to decreased usage among youth, with an increase in suicide attempts and deaths observed.

A study of > 14,000 patients offers insights on real-world usage and characteristics of new rimegepant users, showing distinct patterns in acute vs. preventive treatment.

A study shows secukinumab clears skin lesions faster than ustekinumab in generalized pustular psoriasis, with improved responses observed by week 2.

Crisugabalin at 40 mg/d or 80 mg/d significantly reduced daily pain in adults with postherpetic neuralgia, a phase 3 study found.

Triptans, including eletriptan and sumatriptan, offer better migraine relief than newer, more expensive drugs, suggesting they should be first-line treatments.

A study reveals that individuals with schizophrenia spectrum disorders experience high rates of comorbid mental health conditions and receive minimally adequate treatment.

A recent study found that after 2019, the combined cost of fatal falls among people aged ≥ 45 exceeded firearm injury costs, highlighting the economic burden of senior falls.