Giuliana Grossi

A comprehensive literature review supports the association between sleep disorders and chronic migraine, leading to poor quality of life, loss of workforce and economic burden.

Catherine Nester, RN, and Dr. Stephen Kingsmore, discuss the pivotal role of newborn screening in diagnosing rare diseases along with the impact that BeginNGS can have on the future of rare disease medicine.

"Especially when untreated and in late stages of progression, ILD is well known to impact health related quality of life," according to Dr. Briana DiSilvio. "Chronic dyspnea, cough, and reduced exercise capacity can become disabling."

Breaking phase 3 data were just announced from the results of the daridorexant (Quviviq) clinical trial for adults with insomnia in Japan.

A profound escalation in the frequency of nightmares, independently associated with suicide risk, occurred alongside related sleep and mental health outcomes during the COVID-19 pandemic.

The FDA granted a Priority Review to the leniolisib New Drug Application (NDA) indicated for individuals with activated phosphoinositide 3-kinase delta syndrome (APDS) 12 years and older.

The research examined how anxiety and pre-bedtime behaviors that are often reported in primary care settings impact sleep health and discussed targeted interventions for effective treatment.

The study explores the relationship between the ascending arousal network, its alterations, and its connections with cortical networks in chronic insomnia disorder.

A majority of individuals who received one of the various cannabinoid products experienced a significant improvement in sleep quality and duration.

Conflicting evidence on the risks associated with intubation in patients with COVID-19 initiated a debate in the medical community regarding the benefit of utilizing high-flow oxygen.

Dr. Craig Granowitz of Lexicon Pharmaceuticals details the success of the LX9211 clinical trial for painful diabetic neuropathy and the unique study design.

"Collectively, this work highlights and supports chronotype as a potential risk factor related to type 2 diabetes and cardiovascular disease risk," investigators wrote.

Various consequences have been linked to nightmares and can have a severe impact on mental health, even leading to increased risk of suicide.

New evidence from a Mount Sinai study suggested that consistent lack of sleep has negative effects on immune stem cells and increases the risk of inflammatory disorders and heart disease.

Dr. Steven Pipe talks about the profound effect the novel recombinant factor VIII candidate demonstrated in patients with hemophilia A.

"We've never had any prophylactic therapy that maintains patients at this level of hemostatic protection well into the normal range for the majority of the week," Dr. Steven Pipe says.

LX9211 is a potent, orally delivered, selective small molecule inhibitor of adaptor-associated kinase 1 (AAK1).

Short and long nighttime sleep duration, along with daytime napping, were associated with a moderate increase in risk of cardiovascular diseases.

Evidence has suggested a relationship between screen time and poor sleep among youth, however, little evidence has been provided for adults.

Mother's who follow the DASH dietary pattern experience better sleep health for themselves and their infants, according to new study.

When compared to traditional in-lab polysomnography, the Circul ring-worn oximeter produced similarly reliable results in detecting obstructive sleep apnea (OSA).

New data, alongside any future research operating from a family systems approach can provide novel insight into sleep, mental health, and attachments.

Patients with pulmonary tuberculosis (TB) exhibited an improvement in quality of life and a reduction in treatment costs by utilizing a digital medication event reminder monitor (MERM).

Dr. Sara Mednick's pursuit to understand how to improve intelligence led her to an extensive career of studying the various mechanisms of sleep.

Dr. Mednick's latest book, The Power of the Downstate, focuses on the integrated role of sleep by following the "rhythm of upstates and downstates" that people operate in every day.

Cases and hospitalizations due to EV-D68, a rare form of enterovirus associated with acute flaccid myelitis (AFM), have been increasing among children across the country.

Nonpharmacological sleep interventions that focused on earlier sleep schedules can serve as a “simple, pragmatic, effective way to meaningfully increase sleep duration that could have important benefits for child health.”

Acadia Pharmaceuticals announced that the FDA granted a priority review for trofinetide and set March 12, 2023 as the PDUFA date.

The FDA accepted the Biologics License Application (BLA) and granted priority review for velmanase alfa, an investigational enzyme replacement therapy intended to treat the ultra rare disease.

DaxibotulinumtoxinA-lanm (Daxxify) is the first and only neuromodulator stabilized with Peptide Exchange Technology (PXT) and addresses the treatment duration effect.