Sparsentan Could Address Unmet Need in Focal Segmental Glomerulosclerosis Population
Therapeutic candidate Sparsentan could expand treatment options for 2 rare kidney diseases. Dr. Jula Inrig expands on the potential for the FSGs patient population.
Research Identifies Sleep Habit That's Linked to Diabetes Risk
A study published in Diabetologia discovered that individuals who are exposed to high light pollution while they sleep show a greater risk of developing type 2 diabetes.
The Future of Sparsentan According to Travere Therapeutics Chief Medical Officer
Dr. Jula Inrig explains the mechanism of action for the Dual Endothelin Angiotensin Receptor Antagonist (DEARA) investigational candidate Sparsentan, for rare kidney diseases.
New Obstructive Sleep Apnea Screening Recommendation Highlights Gap in Sleep Medicine
Sleep Medicine Expert Daniel Gottlieb, MD, MPH, details a response to the USPSTF screening recommendations for obstructive sleep apnea in a primary care setting.
Updated Recommendations for Obstructive Sleep Apnea in General Population
US Prevention Services Task Force (USPSTF) announces that after reviewing the clinical utility of obstructive sleep apnea screening tools in a primary care setting, there's insufficient evidence to determine the balance between benefit and harm.
Cognitive Behavioral Therapy Improves Insomnia in Patients with Primary Brain Tumor
Cognitive Behavioral Therapy (CBT) for insomnia is the front-line treatment for sleep disturbance. However, the effectiveness of this approach for those with primary brain tumors hasn't been evaluated until now.
Smart Bed Technology and the Future of Sleep Science
"Having the ability to enhance the sleep quality in a way that is scientifically important, and also taking into account objective measurements opens a lot of possibilities," Gary Garcia-Molina, PhD, said in an interview.
New Research Reveals Critical Need to Improve Sleep Health in US
Because unhealthy sleep is associated with multiple conditions and higher risk of mortality, investigators call for further research on the potential to optimize overall sleep health in the US.
How do Smart Beds Capture Clinical Data?
Gary Garcia-Molina, PhD, explains precisely how Sleep Number smart bed technology works after conducting multiple sleep studies.
Caregivers of Individuals With Phelan-McDermid Syndrome and FDA Discuss Treatment Potential
Nonprofit organizations combined efforts to plan a meeting to inform and educate the FDA and key stakeholders about the experience of caregivers and patients with Phelan-McDermid syndrome (PMS).
Gary Garcia-Molina, PhD, Talks About How Smart Bed Technology Enhances Pediatric Sleep Research
At the International Pediatric Sleep Association (IPSA) Congress 2022, investigators from Sleep Number presented 2 investigations that utilized its smart bed technology to analyze pediatric sleep behaviors.
Jula Inrig, MD: New Data on the Burden of Immunoglobulin A Nephropathy
Dr. Jula Inrig highlights the key data presented at ASN Kidney Week on investigational candidate Sparsentan for IgA nephropathy.
Black Veterans With Chronic Kidney Disease Experience Earlier Onset, Higher Risk of Kidney Failure
Investigators evaluated how the risk of kidney failure and death affects US veterans with chronic kidney disease (CKD) in research presented at Kidney Week 2022 ASN Annual Meeting.
Study Links Kidney Disease With Silent Stroke, Dementia, Cognitive Impairment
New research presented at Kidney Week 2022 ASN Annual Meeting, demonstrates an association between albuminuria and risk of cognitive problems.
Phase 3 Data Provide Evidence of Voclosporin as Long-Term Treatment for Lupus Nephritis
A significantly higher number of patients receiving voclosporin achieved good renal outcome when compared with placebo.
Marked Increase of Studies on Chronic Kidney Disease Show a Focus on Targeted Biological Treatments
In the last 20 years, most were adult studies which indicates a need for pediatric research activity, especially considering the potential that targeted therapies have for treating chronic kidney disease in children.
Large-Scale Data Collected from Smart Bed Technology Show Sleep Differences in Pediatric Groups
New data from the International Pediatric Sleep Association (IPSA) Congress 2022 used smart bed technology that revealed consistent findings to previous studies.
New Patient Assessment on Stigmatization of Visible Skin Conditions is Validated
Evaluating the stigma associated with various dermatologic conditions is more accessible with the validated PUSH-D questionnaire.
FDA Defers Action on Novel Pompe Disease Therapy Cipaglucosidase Alfa, AT-GAA Decision
Aside from the inability to fulfill the site inspection, there was no other reason for the FDA deferral. The approval of the combination drug candidate's 2 components are still expected.
Rare Disease Report Podcast: FDA Reviews Combination Therapy for Pompe Disease
The Pompe disease community is anticipating the pivotal FDA decision for AT-GAA, a combination therapy for late-onset Pompe disease (LOPD) that has the potential to expand the armamentarium of physicians.
When to Opt for Imaging When Presented with Pain, Early Onset Hypertension
Dr. Neera Dahl explains that patients with autosomal dominant polycystic kidney disease (ADPKD) are often referred to a nephrologist when imaging is done for another concern.
Insomnia Treatment Can Mitigate Symptoms in People With Bipolar Disorders
Depressive disorders are often accompanied by low levels of resilience and research indicates that targeting insomnia symptoms could address the severity of these psychiatric disorders.
Neera Dahl, MD, Identifies how to Diagnose Autosomal Dominant Polycystic Kidney Disease
The common inherited condition autosomal dominant polycystic kidney disease (ADPKD) remains elusive when presented in primary care due to its nonspecific symptoms.
Coexisting Insomnia and Sleep Apnea Lead to Fatal Outcomes
Investigators are urging for more research on the mechanisms involved with comorbid insomnia and obstructive sleep apnea (OSA) to reduce the mortality risk in patients with both sleep disorders.
Paroxysmal Nocturnal Hemoglobinuria Drug Candidate Demonstrates Superiority to Anti-C5 Therapies
Iptacopan has the potential to address an unmet need in PNH by significantly increasing hemoglobin levels in patients who remain anemic, fatigued and dependent on blood transfusions after anti-C5 treatment.
Facial Moisturizer with SPF35 Formulated for Skin of Color is Clinically Supported
The moisturizer was designed to address concerns regarding the suitability of sunscreens for individuals with skin of color and show the importance of "aesthetic elegance” to increase sunscreen utilization.
Exacerbation Prevention: Research Highlights Unmet Need in Bronchiectasis Treatment
Data from NORD Breakthrough Summit 2022 support the need for exacerbation prevention among patients with bronchiectasis, a rare chronic condition.
New Rare Disease Therapy Effectively Lowers Plasma Phe in Patients with PKU
Top-line data comparing 2 strains of a non-systemically absorbed drug candidate was announced this morning, with SYNB1934 expected to advance to a phase 3 clinical trial.
Can Intranasal Corticosteroids Improve Obstructive Sleep Apnea Syndrome in Children?
A study featured at CHEST 2022 investigated INCS in children with OSAS to determine if the therapy improved their symptoms, polysomnography findings, behavior, and quality of life.
Pri-Med Midwest Highlights: Diabetes, Obesity Management & GLP-1 RAs
The emergence of weight loss agents like tirzepatide and an FDA Fast Track designation announced days earlier, endocrinologists were excited to discuss what's happening at Pri-Med Midwest 2022.
2 Clarke Drive Cranbury, NJ 08512