Paul A. Heidenreich, MD, MS2: From the 1Stanford University Hospital, Falk Cardiovascular Research Center, Stanford, CA

There is some debate about whether the risk of cardiovascular events associated with low high-density lipoprotein (HDL) cholesterol levels is attenuated by very low low-density lipoprotein (LDL) cholesterol levels (< 60 mg/dL), which can be obtained with statins and combination therapy.