Clinical Pearls for the Management of ALGS
Experts in pediatric hepatology share advice for the optimal management of Alagille syndrome.
Patient Education and Future Directions for ALGS Management
Drs Ryan T. Fischer and Regino Gonzalez-Peralta provide insight on educating patients and their caregivers on emerging treatment options for Alagille syndrome and the potential impact of evolving therapies on the progression of liver disease.
Unmet Needs and Novel Agents for the Management of ALGS
Jennifer M. Vittorio, MD, and Philip Rosenthal, MD, comment on remaining challenges for the management of patients with Alagille syndrome and discuss novel therapeutic agents under investigation for disease management.
Using Maralixibat for the Management of Pediatric ALGS
Regino Gonzalez-Peralta, MD, reviews clinical implications from the phase 2 ICONIC trial evaluating the use of maralixibat for the management of Alagille syndrome in pediatric patients.
Treating Persistent Pruritus for ALGS
Jennifer M. Vittorio, MD, leads a discussion on initial treatment approaches and new drugs on the horizon for the management of persistent pruritus in patients with Alagille syndrome.
Individualizing Treatment Approaches for ALGS Management
Drs Ryan T. Fischer and Regino Gonzalez-Peralta highlight the importance of tailoring treatment to a patient’s symptoms and define treatment success for Alagille syndrome.
Goals of Therapy for ALGS
Jennifer M. Vittorio, MD, reviews goals of therapy from early disease through progression of Alagille syndrome.
Monitoring Nutrition and Progression of ALGS
Philip Rosenthal, MD, examines monitoring requirements and follow-ups for patients with Alagille syndrome.
Multidisciplinary Management of ALGS
Regino Gonzalez-Peralta, MD, explores the role of a multidisciplinary approach to the diagnosis and management of patients with Alagille syndrome.
Clinical Outcomes and Management of ALGS
Experts in pediatric hepatology review health complications associated with ALGS and the importance of early diagnosis to manage the disease.
Patient Journey to ALGS Diagnosis
Philip Rosenthal, MD, discusses his approach to the diagnostic workup for Alagille syndrome.
Clinical Burden of ALGS for Pediatric Patients
Regino Gonzalez-Peralta, MD, provides insight on quality-of-life issues for patients and caregivers with Alagille syndrome.
Clinical Presentation of ALGS
Drs Ryan T. Fischer, William Balistreri, and Regino Gonzalez-Peralta comment on the clinical variability in the presentation of Alagille syndrome in patients.
Overview of Alagille Syndrome (ALGS)
Philip Rosenthal, MD, leads an overview of Alagille syndrome and discusses the role of genetic testing in the screening and diagnosis of disease.
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