Authors

Failing with women: How clinical trials fail our largest subgroup

The current guidelines for the management of heart failure in women are based upon data collected from studies predominantly enrolling men. However, because important differences exist in the sex-based pathogenesis of and prognosis for heart failure, the current risk-benefit analyses that guide the evidence-based management of heart failure in women demands prospective assessment.

Pioglitazone and recurrent myocardial infarction in patients with diabetes and a previous myocardial infarction

We analyzed a subgroup of 2445 subjects with diabetes, macrovascular disease, and previous myocardial infarction (MI) from the Prospective Pioglitazone Clinical Trial in Macrovascular Events to determine the effects of pioglitazone on mortality and macrovascular morbidity. Pioglitazone was shown to decrease the occurrence of adverse cardiac outcomes, including recurrent MI, in these high-risk subjects. This additional benefit of pioglitazone in patients with diabetes and a previous MI suggests that it may be appropriate to include this medication in the management strategy of patients with MI.

Don't Bail Out of the Stock Market Yet

Grand Bahama Island

The Dangers of Health Disparities and the Urgent Need to Address Them

Benefits and Drawbacks of Clopidogrel 600mg Double Loading Dose Versus Newer P2Y12 Receptor Blockers

Prolonged dual antiplatelet therapy With aspirin and clopidogrel is recommended for all patients undergoing percutaneous coronary intervention.

C. Diff Foundation Highlights Latest Advances in the Battle Against the Deadly Pathogen

CDC official is hopeful they can beat C diff infection.

Are HDL cholesterol levels clinically significant in patients with low LDL cholesterol levels?

There is some debate about whether the risk of cardiovascular events associated with low high-density lipoprotein (HDL) cholesterol levels is attenuated by very low low-density lipoprotein (LDL) cholesterol levels (< 60 mg/dL), which can be obtained with statins and combination therapy.

Cinema Consults: SEABISCUIT

Are Your Patients in Clinical Trials? US Oncology Surveys Oncologists

Participation in clinical trial research is essential to continued improvement in cancer care. Yet, fewer than 10% of U.S. adults enroll in trials. A recent US Oncology�sponsored survey found that most oncologists remain optimistic about the future of clinical trial research. We discuss obstacles to clinical trial enrollment with Nicholas Vogelzang, MD, and Matthew Galsky, MD, of the Comprehensive CancerCenters of Nevada.

Alternating Hemiplegia of Childhood: Partnering with the Patient

Since AHC is a rare neurological disease, finding a diagnosis can be a harrowing experience.

Improving Your Patients' Adherence to Statin Therapy

Despite the proven benefits of lipid-lowering therapy, many patients stop taking their prescribed medications. Follow these practical tips to increase patients' compliance.