Expert Perspectives on the Optimal Management of Sickle Cell Disease

Wally Smith, MD, and Abdullah Kutlar, MD provide an overview of sickle cell disease and its pathophysiology.

Experts discuss the prevalence and burden of sickle cell disease.

Key opinion leaders give insight on the presentation of sickle cell disease, also highlighting acute vs chronic complications of the disease.

Abdullah Kutlar, MD, reviews the guideline recommendations for screening and monitoring of anemia-related sickle cell disease manifestations.

Clinicians dive into the impact of sickle cell on quality of life and symptom management

Patrick McGann, MD, MS, reviews the role of hydroxyurea in sickle cell disease, touching on the mechanism of action and expected outcomes.

Wally Smith, MD, discusses L-glutamine in the treatment of SCD.

Insight on the screening and monitoring for red blood cell transfusion for the management of sickle cell disease.

Experts discuss the considerations, as well as a specific case in patients receiving hemopoietic stem cell transplant (HSCT).

Abdullah Kutlar, MD, reviews the benefits and risks of treating patients with hemopoietic stem cell transplant.  

Looking at voxelotor in sickle cell disease, experts review the HOPE study.

Wally Smith, MD, gives insight on using voxelotor in patients during the COVID-19 pandemic.  

Key opinion leaders focus on the use of crizanlizumab for painful crisis frequency in sickle cell disease.

Experts discuss patient factors and decision-making in choosing therapies for sickle cell disease.

An overview of gene therapy in sickle cell disease as well as clinical trials underway in the space.

Experts review data around emerging gene therapy approaches in sickle cell disease.

A discussion of the course of gene therapy compared with stem cell therapy.

Key opinion leaders dive into global challenges in sickle cell disease while focusing on treatment access.

Experts look into what is next for sickle cell disease and provide key thoughts on the space.