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This Year In Medicine 2025

Opinion|Videos|February 17, 2025

Considerations for Switching Systemic Agents in Atopic Dermatitis

Panelists discuss the prevalence of treatment-refractory moderate to severe atopic dermatitis, noting factors such as intolerance or inability to use high-potency topical agents as common reasons for treatment failure, and emphasize the importance of considering alternative agents or switching treatments when necessary, particularly in pediatric patients, with biologics and Janus kinase (JAK) inhibitors being key options as evidenced by studies such as Blauvelt 2023, Keow & Abu-Hilal 2024 , and JADE EXTEND.

Episodes in this series

3 experts are featured in this series.

EP. 1 Overview of Atopic Dermatitis Pathophysiology and Atopic March in Children

3 experts are featured in this series.

EP. 2 Considerations for Diagnosing Atopic Dermatitis and Assessing Severity

3 experts are featured in this series.

EP. 3 Exploring the Pediatric Patient and Caregiver Journey

3 experts are featured in this series.

EP. 4 Multidisciplinary Approaches to Atopic Dermatitis Management and Referrals

3 experts are featured in this series.

EP. 5 Setting Goals for Pediatric Atopic Dermatitis Treatment

3 experts are featured in this series.

EP. 6 Real-World Challenges to Providing Evidence-Based Care for Atopic Dermatitis

3 experts are featured in this series.

EP. 7 Navigating New Treatment Options for Pediatric Atopic Dermatitis Management

3 experts are featured in this series.

EP. 8 Managing Comorbidities and Mitigating Atopic March in Adolescent and Adult Patients

3 experts are featured in this series.

EP. 9 Expectations for Efficacy and Duration of Response With Systemic Atopic Dermatitis Treatments

3 experts are featured in this series.

EP. 10 Considerations for Switching Systemic Agents in Atopic Dermatitis

3 experts are featured in this series.

EP. 11 Future Directions in the Treatment of Pediatric Atopic Dermatitis

3 experts are featured in this series.

EP. 12 Patient and Caregiver Advice for Navigating Atopic Dermatitis

3 experts are featured in this series.

EP. 13 Key Takeaways on the Evolving Landscape of Pediatric Atopic Dermatitis Treatment

Video content above is prompted by the following:

How prevalent is treatment-refractory moderate to severe atopic dermatitis?
What are other reasons for treatment failure (eg, intolerance, inability to use high-potency topical agents)?
When do you consider adding or switching agents?
What other treatment options exist for pediatric atopic dermatitis?
How do you determine which treatment to switch to?
Biologic to JAK inhibitor: Blauvelt 2023, Keow & Abu-Hilal 2024, JADE EXTEND, Shi 2022

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