HCV Treatment Success Doesn't Depend on Specialists
Patients with HCV infection achieved the same rates of sustained virologic response regardless of whether they were treated by a specialist or non-specialist provider.
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Despite Benefits, MS Patients Underutilize Exercise
Exercise has shown potential to improve symptoms, restore function and increase quality of life in multiple sclerosis patients.
Veterans Affairs Aims at HCV Infection Cure
The VA declares it is "poised to share" its methods and success in reaching and treating patients with HCV.
Novel Assay Distinguished Bacterial from Viral Infections
A novel assay of host-based biomarkers can help determine whether children have bacterial or viral infections
NIAID Assures Standards Maintained in Rush to Develop Ebola Vaccine
A newly published phase 2 trial described a unique collaborative effort to test 2 candidate vaccines in Liberia against the 2013 Ebola outbreak.
ReBUILD Trial Demonstrates Remyelination in MS
The first randomized controlled trial of a treatment to restore myelin in the MS patient CNS succeeded with an over-the-counter drug.
Ribavirin Plasma Levels Predict SVR for Hepatitis C Infection
Ribavirin steady-state plasma level rather than weight-based dose was found to be an independent predictor of sustained virologic response in patients with HCV.
Another Investigational Vaccine Fails to Reduce RSV Infections
The potential vaccine for respiratory synctial virus infection in older adults demonstrated immunogenic activity, but without clinical effect.
HIV Treatment Milestones: 2-Drug Regimen in Long-Acting Injection
An anti-HIV 2-drug long-acting injection with comparable antiviral activity to a daily oral triple-drug combination could reduce treatment burden and improve adherence.
First mRNA Vaccine Holds Great Promise
The first trial of an mRNA vaccine against an infectious disease in humans could portend faster productions of more stable vaccines.
Seeking Shorter, Simpler Treatments for HCV Genotype 1
Direct acting antiviral regimens are approved to treat HCV genotype 1 over 12 to 24 weeks, but recent trial results suggest 8 weeks could be sufficient.
Ultra-Rapid HIV Testing Possible With Smartphone App
A breakthrough technology delivers HIV blood test results in seconds with a smartphone-connected biochip.
Effective Influenza Vaccine for Elderly Remains Elusive
The elderly continue to be most affected when the flu strikes, and new research points to a strain most likely to cause hospitalization.
HCV Treatment Not Associated with Liver Cancer, New Evidence Suggests
Findings from an assessment of HCV treatment in over 62,000 patients refutes the suggestion that treatment with DAAs promotes recurrence of HCC.
The Investigation of Amebic Meningoencephalitis from Whitewater Park
A CDC epidemiologist provides details of investigating the case of a "brain-eating" amoeba contracted in a whitewater recreation park.
HIVMA Releases New Guideline for Chronic Pain in HIV
A new guideline from the Infectious Diseases Society of America addresses management of chronic pain in patients living with HIV.
New MAB with Unique Site of Action Investigated for Uncontrolled Asthma
Tezepelumab targets onset of inflammation in evidencing promise for adults with uncontrolled asthma.
Atrial Fibrillation Complicates Treatment, Monitoring of Heart Failure
Omalizumab Asthma Trials Analyzed to Identify Best Responders
Analysis of omalizumab trials has identified asthma patients who are most likely to respond to treatment.
"Real World" Omalizumab Asthma Study Links Response to FeNO
Results from "real word" asthma treatment with omalizumab correspond to clinical trial findings and suggest that FeNO values can help predict treatment response.
HCV Drug Resistance: Infrequent, and Frequently Overcome
Hepatitis C drug treatment resistance can be met and defeated by longer treatment or additional agent.
Surrogate for Asthma Exacerbation Helps Treatment Development
The marker could serve in treatment trials in lieu of participants prone to exacerbation and the accompanying morbidity and risk of death.
Bronchial Thermoplasty Comparable to Omalizumab for Severe Asthma
Bronchial thermoplasty was found comparable to omalizumab in an indirect comparison of their effectiveness for uncontrolled, severe asthma.
Drug Quartet Cocktail Proves Effective for HCV Genotype 3
A triple combination of hepatitis C agents administered with another manufacturer's direct acting antiviral overcomes most difficult-to-cure Genotype 3.
Reconsidering the Role of Inhaled Steroid for Early Childhood Asthma
Inhaled corticosteroid for wheezing in early childhood is effective in selected patients but does not prevent progression to asthma.
Comprehensive Asthma Interventions Effective in Real-World Communities
The CHAMPS study demonstrated that comprehensive asthma interventions proven efficacious in controlled trial settings can be effectively implemented in diverse communities.
Asthma Patients Worsen Without Specialist Referral
Are asthma patients being mismanaged when treatment guidelines on specialist referrals are overlooked?
Azithromycin Not Helpful for Preschool Children with Wheezing
Preschool children presenting to emergency departments for wheezing did not benefit from the addition of azithromycin to symptomatic treatment.
Severe Asthma Remains Burden After Decade of Treatment
A 10-year follow-up of patients with severe asthma finds persistent illness remains difficult to treat.
Closing the Gap: HCV Program Extends to Hard-To-Reach Patients
An integrated care program successfully extended HCV treatment to patients not well served by traditional outreach efforts.