Multiple Sclerosis

Multiple sclerosis can lead to seizures. Researchers found the mechanism.

In multiple sclerosis, limited leg function predicts decline.

Perrigo has sold its royalty rights to an important MS drug.

Oral contraceptives do not worsen multiple sclerosis and may help stop relapses.

Off-label use of Ritalin for MS did not help patients.

Placebo did better than promising drug in treating MS fatigue.

Loss of sense of smell predicts more severe multiple sclerosis.

Diagnosing pediatric MS: more accurate with test refinements.

People with multiple sclerosis tend to have sleep apnea, but not the usual kind, a study found.

Researchers have been studying the potential multiple sclerosis drug ocrelizumab (Ocrevus/Genentech) for years. Results from those studies have been published in the New England Journal of Medicine (NEJM).

Physicians have long been concerned that patients with multiple sclerosis who get frequent brain scans accumulate deposits of the rare earth used as a contrast agent, gadolinium. German researchers found an alternative agent.

Patients with multiple sclerosis may have excess iron in their brains, a possible explanation for brain atrophy, the debilitating condition some develop. If so, the culprit is likely leaky red blood cells, a UK team reported.

Patients with intermediate uveitis (IU) have a high likelihood of achieving good long-term visual outcomes, but should expect a long disease course and frequent complications

For many patients who are vitamin D deficient, there are oral supplements which can be found over the counter which can help bring their levels into the normal range. That and other steps can help play a role in lessening the risk of developing multiple sclerosis.

Whether patients need to move to stronger medications, or find a more effective treatment, doctors need as much information as possible before making a decision on what course to follow.

Bryan Bickell, a three-time Stanley Cup winner, has turned to former goalie Josh Harding for guidance on how his new diagnosis will impact his life and career. Harding continued to play in the league for two seasons following his own multiple sclerosis diagnosis in 2012.

Curiouser and curiouser. Like Alice in Wonderland, when Alan Thompson, MD, first entered multiple sclerosis research, he was deeply puzzled. But he kept going deeper.

The common multiple sclerosis treatment, according to a study out of Duke, may do very little for as many as half of people with the disease. In a mouse model of MS, they identified different disease pathways in those resistant to the treatment, raising questions about the heterogeneity of MS.

Cortical lesions in MS have clinical relevance.

The authors assert that “there remains a need to identify inexpensive and non-toxic therapies that target the underlying pathophysiology of autoimmune disorders” and that “Blockade of the opioid growth factor (OGF)-OGF receptor (OGFr) pathway with low dose naltrexone (LDN) has been explored as one such therapy.”

Sudden hearing loss is a rare but real potential complication in multiple sclerosis.

Patients with relapsing remitting multiple sclerosis (RRMS) who have T2 spinal cord (SC) lesions detected through magnetic resonance imaging (MRI) early in the course of the disease are likely to have a worse prognosis, according to recent research.

Patients with multiple sclerosis (MS) who want or need to measure their daily step-count may get the most accurate results with the waist-worn FitBit One, researchers found.

There are many ways of figuring out what stage of illness a patient with MS is experiencing and if relapse is likely. Researchers evaluated several.

There has been plenty of research to show that rehabilitation can help with the cognitive function of patients with multiple sclerosis. A recent study looked at whether advanced imaging can determine whether some patients will respond better to the therapy than others.