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Malignant hyperthermia is a potentially fatal disorder usually associated with administration of certain general anesthetics and/or succinylcholine. Until 30 years ago, its etiology was unknown. Then, researchers found that people who carry an autosomal dominant calcium channel mutation are at elevated susceptibility.

Pharmacologic approaches are still "the most widely used therapeutic options to ameliorate persistent pain," according to this overview from UpToDate. But with growing awareness of the potential negative outcomes associated with long-term opioid therapy, a newly discovered approach may be just what the doctor ordered.

A Canadian company announced it would invest $100 million (US dollars) in Jamaican marijuana research and development. A Colorado company also plans to invest there. Though marijuana has long been grown in Jamaica and exported illegally, the island's government decriminalized medical use in February.

Women suffering from primary dysmenorrhea – painful menstruation in the absence of any sort of pelvic pathology – are unlikely to think much of it, chalking it up to a normal part of the menstrual cycle. A review in Human Reproduction Update, however, suggests that health professionals and pain researchers also generally ignore the condition.

Cardiovascular patients are the focus of the recent drug approval by the Food and Drug Administration (FDA). Branded under the name Durlaza, the 24-hour extended-release aspirin is the first of its kind and is expected to become available before the end of the year.

Researchers in Brazil recently noted that marijuana use may mitigate some of the more severe psychiatric side effects associated with crack cocaine addiction, potentially making it easier for addicts to stop using the drug.

Trigeminal neuralgia is often mistreated or under-treated. Even when treatment is appropriately delivered, there can be troublesome side effects and complications. Proper diagnosis and treatment typically involves coordination of care among neurologists, anaesthesiologists, dentists, neurosurgeons, and neuroradiologists