Pulmonology

The new recommendations buck against the organization's prior guidance, noting the variability of reported race and ethnicity that applies to clinical assessment.

New data demonstrate a concerning link between particulate matter ≤2.5 μm exposure and the risk of prolonged symptoms of COVID-19 in young adults.

A new cohort study suggested the number of days per week taking 8000 steps or more was associated with a decreased risk of all-cause and cardiovascular mortality.

Future research could explore the factors contributing to this disparity and identify effective interventions to reduce tobacco use in this population.

Investigators developed and validated a tool for daily assessment of asthma control that can be utilized in clinical trials as an endpoint.

As the US tries to move on from the pandemic, patients with long COVID-19 are fighting to regain normalcy while clinicians improve care plans and researchers search for answers.

The ANTICOVID clinical trial finds high-dose prophylactic anticoagulation reduces risk of de novo thrombosis in COVID-19 pneumonia.

The results of a comprehensive meta-analysis indicate a high prevalence of comorbidities among asthma patients, emphasizing the importance of effective treatment strategies.

Data also show significant improvements in quality of life and respiratory symptoms in patients with evidence of type 2 inflammation who were treated with dupilumab.

Where access to healthcare is limited, the impact of diagnostic bias based on skin tone can result in a greater burden of disease and even more deaths, especially for Black individuals.

Personalized text message-based smoking cessation intervention was found to be more effective than the non-personalized text message approach, especially among smokers with low nicotine dependence and strong quitting intention.

An investigation utilizing machine learning (Recursive Ensemble Feature Selection, REFS) identifies potential biomarkers for asthma control in pediatric patients.

Practicing oral hygiene improves health issues from gum disease to cardiac disease, and Lebovic believes nasal hygiene can have that impact as well.

In addition to sharing how a novel machine learning method may one day soon predict lung disease susceptibility, Kalhan describes the science behind the ALA Lung Health Cohort Research Study.

At ACC 2023, Hoeper provides insight into the key efficacy findings of STELLAR and delves into the safety concerns and generalizability of sotatercept for PAH.

A one-of-its-kind assessment of 8 decades' worth of UK data show a lower respiratory tract infection by age 2 increases risk of premature adult death by 93%.

Results from the phase 3 A DUE study suggest a combination of macitentan and tadalafil nearly doubled reductions in pulmonary vascular resistance in patients with PAH.

Data from the phase 3 STELLAR trial indicate adding sotatercept to background therapy in PAH was associated with statistically significant improvements in 6-minute walk distance and 8 of the trial's 9 secondary endpoints, including time to death or clinical worsening.

Approximately 42% of prodrome-associated DEGs were also associated with hereditary angioedema attacks, indicating that multiple enriched gene networks with common hub genes and upstream regulators are shared between the prodromal and acute attack stages.

In a presentation at the AAAAI 2023 Annual Meeting, new data suggested that treating early symptoms may be a viable strategy for preventing acute attacks in patients with hereditary angioedema (HAE).

"We are looking at trying to satisfy a truly unmet medical need," Dr. David Dworaczyk says about the development of a new epinephrine nasal spray for anaphylaxis.

Bryn Pharma CEO shares promising data on a novel intranasal epinephrine spray called Utuly during the AAAAI 2023 Annual Meeting.

A study from the AAAAI 2023 Annual Meeting reveals racial and ethnic disparities in the management of severe asthma and highlights the need for interventions to improve care escalation for Black and Hispanic/Latino patients.

Investigators call for further research focusing on refining candidate selection for screening, improving the accuracy of LDCT scan reading, and integrating clinical risk models, imaging techniques, and biomarker research to enhance the probability evaluation of pulmonary nodule malignancy.

A cohort study of 1.9 million infants links exposure to fine particulate matter (PM2.5) to an increased risk of emergency department visits during the first year of life, with preterm and full-term infants being most susceptible during their fourth and fifth months.