Allergy Month in Review: February 2025

Allergy research experienced notable developments in February, with mixed results in immunotherapy and promising advancements in allergic treatment strategies. A Phase 1/2 trial investigating oral immunotherapy demonstrated increased food allergy thresholds in children with multiple allergies but failed to meet its primary endpoint. Meanwhile, gradual exposure to store-bought peanut butter may be more effective in desensitizing children with peanut allergies than avoidance strategies, adding to the growing discussion on early allergen introduction. Notably, peanut oral immunotherapy has now become available in the US for children as young as one, potentially shifting the paradigm for early intervention.