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Spotlight -

This Year In Medicine 2025

Opinion|Videos|April 10, 2025

Learnings From the VISIBLE Study in Skin of Color

Author(s)Jason Hawkes, MD, MS, Saakshi Khattri, MD, James Song, MD

Panelists discuss how despite limited but encouraging efficacy and safety data from studies like VISIBLE (guselkumab) and various subgroup analyses supporting biologic use across diverse skin tones, clinicians must still consider unique presentations and concerns when treating patients with skin of color, including postinflammatory hyperpigmentation, follicular presentation patterns, cultural perspectives on treatment, and historical underrepresentation in clinical trials, while emphasizing the importance of personalized discussions about treatment expectations and outcomes specific to different skin phototypes.

Episodes in this series

4 experts are featured in this series.

EP. 1 Challenges in Defining Psoriasis Severity in Clinical Practice

4 experts are featured in this series.

EP. 2 Clinical Considerations for Assessing Plaque Psoriasis Severity and Identifying Psoriatic Arthritis

4 experts are featured in this series.

EP. 3 Incorporating Clinical Guidelines in Psoriasis Management

4 experts are featured in this series.

EP. 4 Navigating Biologic Treatment Selection in Psoriasis and Psoriatic Arthritis

4 experts are featured in this series.

EP. 5 Exploring Undertreatment of Psoriasis in Skin of Color

4 experts are featured in this series.

EP. 6 Advancing From Topicals to Systemic Treatment in Psoriasis Management

4 experts are featured in this series.

EP. 7 Learnings From the VISIBLE Study in Skin of Color

4 experts are featured in this series.

EP. 8 Effect of High-Impact Site Involvement on Quality of Life

4 experts are featured in this series.

EP. 9 New Data in Patients With Psoriasis With High-Impact Site Involvement

4 experts are featured in this series.

EP. 10 Applying Learnings From the SPECTREM Study to Clinical Practice

4 experts are featured in this series.

EP. 11 Examining the Relationship Between Psoriasis and Psoriatic Arthritis

4 experts are featured in this series.

EP. 12 Dosing Interval Differences in Psoriasis and Psoriatic Arthritis Treatment

4 experts are featured in this series.

EP. 13 Future Directions for Psoriasis Treatment

Video content above is prompted by the following:

Data, while limited, show that biologics are safe and effective treatment options across skin tones. How do you take these data into consideration when deciding on treatment for your patients with skin of color?
- VISIBLE study—guselkumab
- Various subgroup and post hoc analyses

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