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This Year In Medicine 2025

Opinion|Videos|April 10, 2025

Effect of High-Impact Site Involvement on Quality of Life

Author(s)Jason Hawkes, MD, MS, Saakshi Khattri, MD, James Song, MD

Panelists discuss how treating psoriasis in anatomically challenging areas such as the scalp, face, genitals, intertriginous zones, palms, soles, and nails requires specialized approaches due to unique barriers including limited penetration of topicals, skin sensitivity, mechanical friction, and psychological impact, necessitating tailored treatment strategies that may include modified vehicle formulations, careful steroid use, targeted phototherapy, or earlier consideration of systemic agents including biologics for these high-impact sites even when overall body surface involvement is limited.

Episodes in this series

4 experts are featured in this series.

EP. 1 Challenges in Defining Psoriasis Severity in Clinical Practice

4 experts are featured in this series.

EP. 2 Clinical Considerations for Assessing Plaque Psoriasis Severity and Identifying Psoriatic Arthritis

4 experts are featured in this series.

EP. 3 Incorporating Clinical Guidelines in Psoriasis Management

4 experts are featured in this series.

EP. 4 Navigating Biologic Treatment Selection in Psoriasis and Psoriatic Arthritis

4 experts are featured in this series.

EP. 5 Exploring Undertreatment of Psoriasis in Skin of Color

4 experts are featured in this series.

EP. 6 Advancing From Topicals to Systemic Treatment in Psoriasis Management

4 experts are featured in this series.

EP. 7 Learnings From the VISIBLE Study in Skin of Color

4 experts are featured in this series.

EP. 8 Effect of High-Impact Site Involvement on Quality of Life

4 experts are featured in this series.

EP. 9 New Data in Patients With Psoriasis With High-Impact Site Involvement

4 experts are featured in this series.

EP. 10 Applying Learnings From the SPECTREM Study to Clinical Practice

4 experts are featured in this series.

EP. 11 Examining the Relationship Between Psoriasis and Psoriatic Arthritis

4 experts are featured in this series.

EP. 12 Dosing Interval Differences in Psoriasis and Psoriatic Arthritis Treatment

4 experts are featured in this series.

EP. 13 Future Directions for Psoriasis Treatment

Video content above is prompted by the following:

What are some areas of the body that are particularly challenging to treat in psoriasis? What is your approach to treatment for these areas?

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