Dermatology Care Limited in Rural American Indian Communities
Both brick-and-mortar dermatology clinics as well as telehealth programs are limited and restricted by barriers to access.
Tildrakizumab for Psoriatic Arthritis Shows Promise in Phase 2 Results
Interim results at 24 weeks show that 75.3% of patients treated with tildrakizumab achieved a 20% improvement compared to 50.6% with placebo.
FDA Approves MRI-friendly Cochlear Implant
The new approval allows for easier access to MRIs and direct audio streaming from Android devices.
Tofacitinib for Rheumatoid Arthritis Non-inferior to Combo Therapy
In the phase 3b/4 ORAL Shift study, tofacitinib monotherapy was shown to be comparable to tofacitinib with methotrexate.
FINCH 3 Results: Filgotinib with Methotrexate Outperforms Methotrexate Alone
Patients with rheumatoid arthritis receiving combination treatment were more likely to reach ACR20, ACR50, and ACR70 than those receiving methotrexate monotherapy.
Much Pregnancy-related CVD Risk Associated with BMI, BP
Up to 77% of the increased CVD risk associated with preeclampsia and gestational hypertension is associated with conventional risk factors like BMI and blood pressure.
Risankizumab Provides Long-term Psoriasis Skin Clearance
Results from the phase 3 IMMhance study show that of patients who reached sPGA 0 at week 28, 73% maintained skin clearance at week 94.
Sleep Disorders Common Among Nurses
A survey of nurses at an academic medical center found that 49% averaged less than 7 hours of sleep per night, compared to the national figure of 28%.
Medical Marijuana Laws Likely Don't Affect Opioid Overdose Deaths
Contrary to earlier research, investigators found that medical cannabis laws do not reduce deaths caused by opioid overdoses.
FDA Permits Marketing for IBS Pain Relief Device
The IB-Stim device uses electrical pulses to stimulate cranial nerves and reduce pain associated with irritable bowel syndrome.
Prenatal Antiepileptic Drug Exposure Associated with Childhood Behavior Issues
Children exposed in utero to valproate were most affected, but exposure to 3 other monotherapies were also associated with behavioral issues.
FDA Approves Oral Contraceptive Slynd
The estrogen-free pill allows for a 24-hour missed pill window while maintaining efficacy in preventing pregnancy.
Pulmonary Rehab Rates for African Americans Remain Low
Overall rates of pulmonary rehabilitation rose in areas with greater program density, but rates for African Americans remained low despite greater program density.
FDA Approves Zolgensma for SMA Treatment
This is the first gene therapy approved for a devastating condition that leads to permanent ventilation or death for many patients by age 2.
Lower ED Triage Scores Linked to Antibiotic Delays for Sepsis Patients
Sepsis patients with an acuity score of 3 received antibiotics half an hour later than patients with the slightly more critical score of 2.
Historical Redlining Associated with More Asthma ED Visits
Neighborhoods redlined in the 1930s continue to feel the effects of the racially discriminatory practice, including differences in asthma-related emergency visits.
High Regional Primary Care Use Associated with Less Critical Illness
Increased primary care use in a region was associated with reduced rates of ICU admission and mechanical ventilation use.
Providers Split on Family Presence During ICU Procedures
While 35% of providers say they’re unlikely to allow family to be present during ICU procedures, the 38% who say it’s a regular practice overwhelmingly call it a positive experience.
E-cigarettes May Leave Users Susceptible to Flu, Especially Women
Early research found that e-cigarette use affects the immune system response to the flu virus and the effects are different for female and male users.
Dupilumab Improves Upper, Lower Airway Outcomes in SINUS Trials
Among patients in SINUS-24 and SINUS-52 with chronic rhinosinusitis with nasal polyps and comorbid asthma, dupilumab significantly improved function and patient-reported outcomes.
COPD Risk Score May Help Guide Care Decisions
High-risk LIVE scores for patients with COPD were associated with higher all-cause mortality and higher rates of referral to palliative care.
Budesonide-Formoterol Bests Albuterol in Asthma Exacerbation Prevention
In an open-label trial among adults with mild asthma, budesonide-formoterol treatment was superior to albuterol for the prevention of asthma exacerbations.
FDA Approves Teduglutide for Pediatric Use
Teduglutide (Gattex) has been approved as an injection for pediatric patients 1 year of age and older with Short Bowel Syndrome.
Asthma App Improves Control, Reduces ER Visits
Children with asthma who used the eAsthma Tracker app weekly missed 60% fewer days of school and their parents missed 70% fewer days of work.
After Bariatric Surgery Teens See Improvements in Diabetes, Hypertension
Teens and adults had similar weight loss after gastric bypass surgery, but teens were more likely to experience remission of type 2 diabetes and hypertension than adults.
Uterine Fibroids Successfully Treated with Relugolix Combo Therapy
In the LIBERTY 1 study, daily relugolix combination therapy led to a reduction in menstrual blood loss of 84.3% and improvements in pain and quality of life.
FDA Approves Aflibercept for Diabetic Retinopathy
Aflibercept (Eylea) is an anti-VEGF treatment administered as an intravitreal injection.
FDA Approves sBLA of incobotulinumtoxinA for Blepharospasm
The FDA has expanded the indication for incobotulinumtoxinA (Xeomin) to include treating blepharospasm (involuntary blinking) in adults.
FDA Clears 6-Lead KardiaMobile ECG Device
The KardiaMobile 6L device is the first FDA-cleared 6-lead electrocardiogram (ECG) device for personal use.
Methotrexate Raises Risk of Serious Infections More Than Newer Biologics
Patients with plaque psoriasis taking apremilast, etanercept, and ustekinumab had a lower rate of serious infections than those who took methotrexate.
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