Dedee Murrell, MD: Safety of PRN1008 for Pemphigus Vulgaris
The phase 2 Believe-PV study observed few adverse events in patients with pemphigus vulgaris.
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Patrick Burnett, MD, PhD: Results of CAMP 1 & 2 in Molluscum Contagiosum
Patrick Burnett reports impressive topline results from the CAMP 1 & 2 studies of investigational treatment VP-102.
Dedee Murrell, MD: Significance of the Believe-PV Trial in Pemphigus Vulgaris
Though there are few treatments for pemphigus vulgaris, a rare disease, the Believe-PV trial of PRN1008 raises the possibility of a new, better option.
Hemali Gunt, PhD: Adjunctive Skin Care for Rosacea
Compared to standard cleansers and moisturizers, natural versions for sensitive skin provided benefits to patients with rosacea who were also taking prescription treatments.
Jeffrey Weinberg, MD: Psoriasis Duration Doesn't Impact Brodalumab Success
In this analysis, brodalumab was successful in treating patients who had a psoriasis diagnosis for
Platelet-rich Plasma Improves Hair Loss, Scars, and More
A meta-analysis of studies found that treatment with platelet-rich plasma improves androgenetic alopecia, scarring, and other dermatologic conditions.
Isotretinoin Not Associated with Depression Risk for Acne Patients
A large retrospective study of patients with acne found no significant association between isotretinoin exposure and depression.
Dupilumab Improves Outcomes in SINUS-52
In this phase 3 study, dupilumab improved outcomes for patients with recurring severe chronic rhinosinusitis with nasal polyps.
Eating Peanut After Immunotherapy Linked to Positive Outcomes
Patients who incorporated small amounts of peanut into their diet experienced increased quality of life.
Babies Who Reacted to Allergen Exposure Breastfed Longer
Mothers reported breastfeeding infants who reacted to food allergen exposure via breastmilk for significantly longer than infants who did not react.
Dupilumab Improved Lung Function, Reduced Asthma Exacerbations
This analysis of the phase 3 LIBERTY ASTHMA QUEST study analyzed data for patients with and without allergic rhinitis.
Patient Fears, Records Reduce Penicillin Allergy De-labeling Efforts
Investigators found that age, gender, and allergy test setting were not significantly associated with penicillin allergy label persistence.
Dupilumab Successfully Treats Chronic Rhinosinusitis Nasal Polyps
In a phase 3 study, dupilumab reduced nasal polyp scores and nasal congestion compared to placebo in patients with chronic rhinosinusitis with nasal polyps.
Exclusive Breastfeeding Reduced Odds of Ongoing Eczema At 6 Years
Compared to a short time of breastfeeding or none, children exclusively breastfed for ≥3 months were less likely to have continued eczema at 6 years old.
Asthma More Common in Opioid Dependent Patients, Especially Women
Investigators found that the prevalence of asthma in patients with opioid dependence was more than double the national prevalence.
Wildfires Worse for Children's Immune Health Than Planned Fires
Investigators hope the results will increase public support for prescribed fires that help maintain forest health and prevent wildfires.
Mixed Results from Peanut Allergy Immunotherapy Patch Trial
Results showed a statistically significant difference in responder rate between active treatment and placebo but didn’t meet a prespecified threshold for clinical significance.
FDA Fast Tracks Intranasal Epinephrine Spray
The intranasal epinephrine spray is being developed for use with Intravail, a nasal absorption enhancing technology.
Tanezumab Reduces Chronic Low Back Pain in Phase 3 Study
An investigational non-opioid pain medication, tanezumab demonstrated statistically significant pain reduction at 16 weeks compared to placebo.
William Lennarz, MD: Unique Aspects of a Pediatric ER
William Lennarz, MD, touches on unique aspects of a pediatric ER, including staffing, equipment needs, medication dosing, and working with EMS to improve children's experiences.
William Lennarz, MD: Pediatric Care in the Gulf South
William Lennarz, MD, shares about the positive aspects of providing pediatric emergency care in New Orleans, as well as the challenge of preparing for the next big hurricane.
William Lennarz, MD: Creating a Pain-Free Pediatric ER
William Lennarz, MD, describes the efforts among those in the specialty to reduce pain and anxiety during children's visits to the emergency room.
Linagliptin Non-inferior to Glimepiride on Cardiovascular Safety
The CAROLINA cardiovascular safety study found that linagliptin was non-inferior to glimepiride in time to a composite cardiovascular endpoint.
Esketamine Nasal Spray Gets Support from FDA Advisory Committee
If approved, Spravato would become the first novel mechanism of action in 30 years to treat major depressive disorder.
Counseling Recommended to Prevent Perinatal Depression
The US Preventive Services Task Force has recommended that clinicians refer pregnant and postpartum persons who are at risk of depression for counseling services.
FDA Approves Split Infusion for Daratumumab for Multiple Myeloma
Providers and patients now have the option to choose a first dose of daratumumab in 1 or 2 infusions.
Thirdhand Smoke Residue Impacts Children's Nicotine Exposure
Nicotine was detectable on children’s hands, even when caregivers reported not smoking around the child.
For Quitting, E-Cigarettes Outperform Nicotine-Replacement Options
Smokers assigned to e-cigarettes were more likely to remain abstinent than those offered nicotine-replacements like patches or gum. But questions about vaping safety remain.
FDA Approves Cablivi for aTTP
Cablivi (caplacizumab-yhdp) is the first approved treatment for adults with acquired thrombotic thrombocytopenic purpura (aTTP).
FDA Approves Cablivi for Rare Blood Clotting Disorder