Migraine with Aura Significantly Linked to Incident Atrial Fibrillation
Investigators suggest the findings mean anticoagulants or antiplatelets could potentially treat migraine patients with aura.
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Depression Drug Shows Promise as ALS Treatment on Genetic Level
Trazodone is a depression drug, but it blocks the integrated stress response, so it may be a good candidate for ALS.
Symptom, Visual Outcomes Similar for Both Aflibercept, Ranibizumab
Patients administered either anti-VEGF therapy for nAMD tested similar for improved visual acuity over an observed 12-month treatment period.
Deep Brain Stimulation Treatment for Tardive Dyskinesia Successful in 1 Adolescent Patient
The patient started treatment with resperidone at age 7 but wasn't diagnosed with tardive dyskinesia until age 17.
Engineered Cancer Antivirus Has Antisarcoma Effect
The oncolytic adenovirus was safe in terms of toxicity in mice models.
Therapeutic Target for Medulloblastoma Identified in Mice Models
The medulloblastoma subset has a poor prognosis, so investigators have been looking for new treatment options.
Understanding a Rare Cancer in Duchenne Muscular Dystrophy Patients
There are only 4 case reports of this cancer in muscular dystrophy patients.
Nonelderly Patients Vulnerable 2 Years After C Difficile Infection
For 2 years after C difficile infection, patients under 65 years were at greater risk for gastrointestinal diagnoses compared to uninfected patients.
Common C Difficile Meds Have Similar Outcomes for Severe Infections
Investigators hope their findings will alleviate clinicians’ concerns about choosing between fidaxomicin and oral vancomycin for treatment.
Refining Leukemia Classification for More Accurate Diagnoses
Some of the new subtypes are similar to previously identified ones but show similar prognoses to established subtypes.
Acute Flaccid Myelitis Paralysis Reversed in New Surgery
The surgery restored arm movement and function in children affected by acute flaccid myelitis.
Older Hospitalized Flu Patients Less Likely to Enter ICU
Older age was associated with a lower likelihood of entering the ICU, but increased risk of death for hospitalized patients with influenza.
New Drug to Treat 2 Neglected Tropical Diseases
River blindness and elephantiasis are 2 of the leading causes of global disability.
Muscular Dystrophy Treatment with CRISPR Technology on the Way
Improvements in muscle and cardiac function were observed for 18 months in tested mice.
Metronidazole Successful for Mild C Difficile in Patients Under 65
Success with metronidazole was more likely in patients 65 years and under but was about the same as with vancomycin in those patients.
Unwise to Use Tardive Dyskinesia as an Umbrella Term
More specificity with this group of disorders will help treat them the appropriate way.
Senescent Cell Research Shows Potential for Idiopathic Pulmonary Fibrosis
Only patients with very serious, life-threatening conditions with a risk/benefit ratio is acceptable for use of the therapy at this time.
2017 C Difficile Guidelines Focus on New Treatment Options
The new C difficile guidelines highlight improvements in diagnosing the condition and treating with newer options like fidaxomicin, vancomycin, and fecal microbiota transplantation.
Canadian Pediatric C Difficile Rates Appear Stable
At 10%, recurrence was lower in this analysis compared to other pediatric studies.
Valbenazine Proves Safe and Effective for Tardive Dyskinesia Patients with Mood Disorders
The study focused on patients with bipolar or depressive disorder.
Substance Use Disorder Reduces Antiepileptic Medication Success
A retrospective study showed which patients with substance use disorder may have less successful antiepileptic drug treatment.
Adding Ultraviolet Light to Disinfection Reduces C Difficile Infection
Despite the cost, ultraviolet disinfection helped reduce infection rates in a recent study.
Lacosamide Shows Long-term Efficacy for Newly Diagnosed Epilepsy
Over 2 years, lacosamide was effective and generally well tolerated among adults with newly diagnosed epilepsy, compared to carbamazepine.
Consider Patient and Caregiver Assessments in Tardive Dyskinesia Screenings
Patient and caregiver assessments should be considered alongside clinician assessments during tardive dyskinesia screening procedures, as they may differ.
Clozapine Shows Reduction in Tardive Dyskinesia Symptoms
It remains unclear whether clozapine treats or suppresses the symptoms of tardive dyskinesia.
Chemotherapy Could Elevate Risk for Rare Blood Cancer
While the absolute risk of therapy-related blood cancers is low, the treatment is often intensive and linked to substantial morbidity.
Sutimlimab Demonstrates Efficacy for Cold Agglutinin Disease
In a 10-patient study, sutimlimab halted the destruction of red blood cells in patients with cold agglutinin disease.
Research Shows Emerging Need in AFM Prevention & Treatment
The polio-like AFM is an emerging health concern, with outbreaks documented since 2012.
Adults with Epilepsy Face Differing Contributors to Healthcare Utilization
Investigators found significant differences among patient income quartile zip codes, as well as different age cohorts.
Differences Among Fabry Disease Strains
The classic Fabry disease phenotype in men is almost exclusively marked by anti-agalsidase antibody development, despite having no clear clinical impact.