Atopic Dermatitis

The Regeneron Pharmaceuticals and Sanofi-collaborated biologic became a tour de force in pulmonological care in 2019.

A 48-year-old man presents with severe atopic dermatitis that he’s had since childhood. Can allergy shots succeed where standard treatments failed?

The interleukin pathway-targeting monoclonal antibody has been previously approved for adult atopic dermatitis, and is being considered for a handful more inflammatory or allergic conditions.

Why delving into the symptoms of the most at-need patients is critical for care.

What makes the monoclonal antibody so enticing to the asthma community?

A 200 mg dose of the monoclonal antibody was also shown to significantly reduce ashtma exacerbations over 1 year versus placebo.

In results reported at the European Academy of Dermatology and Venereology Congress, two-week and four-week doses of the subcutaneous drug proved efficacious in improving patient skin.

The patient population tends to have a more unbalanced immune profile to that of European American patients, indicating a potential for tailored treatment options to combat inflammation.

Jonathan Spergel, MD, PhD, and his team linked eosinophilic esophagitis to the condition-based theory. What others are part of the atopic march?

Regeneron has announced that Dupixent, a therapy for adult atopic dermatitis (AD) that is inadequately controlled by existing medications, has been granted marketing and manufacturing authorization in Japan.

Clear or mostly clear skin was achieved by 50/31/14% of patients receiving 30/15/7.5 mg doses of upadacitinib, compared to 2% of patients receiving placebo.

The non-cancerous skin growths currently affect about 83 million US adults.

The New Zealand-based over-the-counter therapy will be available for US patients on Amazon's website in 2018.

Already at war over PCSK9, drug giants go to court over another breakthrough drug.

The second of a two-part, year-end review of advances against eczema/dermatitis (AD) focused on treatment and prevention, noting there was little evidence showing "relative efficacy" of common systemic treatments.

An over-the-counter (OTC) treatment was considered superior to both the corticosteroid and an emollient cream in improving skin hydration.

Previous research showed probiotics given to pregnant women during certain stages of pregnancy and post delivery reduced the likelihood of atopic dermatitis in their children. Recently published reports; however, may not agree.

“While the concept of biofilms in atopic dermatitis is relatively new, antimicrobial and biofilm dispersing agents have been included in the treatment regimen for atopic dermatitis for decades," according to the study authors.

Multiple measurements of skin integrity and function were applied to distinguish between the effects of topical emollient products in a recent study. Two popular products in the UK were determined to transiently improve the skin barrier that is thought to be defective in atopic dermatitis (AD), and another product was confirmed to be damaging.

Researchers report that atopic dermatitis (AD) is associated with increased risk of ADHD in adults and children. Patients with more severe AD were at even higher risk.

A modified Goeckerman regimen was associated with significant improvement of symptoms in patients with chronic, severe atopic dermatitis.

Severe atopic dermatitis (AD) symptoms of shorter duration were more likely to improve in allergen sensitized patients receiving desensitizing immunotherapy, than severe symptoms of longer duration or more moderate symptoms, according to a new observational cohort study.

Childhood atopic dermatitis (AD) usually resolves before adulthood, a meta-analysis of cases showed. Those patients who did see their AD persist were more likely to be female, to have been older at onset, and to have relatively severe AD.

Across the board, researchers saw that studies of active smokers showed increased prevalence of the skin condition, regardless of age or region. It isn't quite clear, though, whether smoking causes AD or AD causes people to smoke.

Topical corticosteroid worked as well as bleach in transforming the microbiota of affected skin to that of healthy skin, an NYU study found.