C Difficile Infection

Experts offered their advice on 2 domains, topic identification and ranking of priorities, for pediatric research realms.

C. diff infections have decreased during the ongoing pandemic.

The estimated the prevalence of C diff infections is about 40 in 30,000 for the sickle cell disease group and about 5000 in 11.8 million for the non-sickle cell disease group.

Longer studies are needed to determine the effectiveness and durability of CDI interventions.

In new data presented at ACG 2020, investigators report on the clinical characteristics and outcomes of chronic pancreatitis patients with CDI.

The CDC has standardized guidelines to help diagnose diarrhea, a potential indicator of c. difficile infection.

The findings also showed that large bedded hospitals trended towards higher clostridium difficile infection incidence and mortality rates.

A poster presented at ACG provides an updated analysis of clostridium difficile infection in the tofacitinib UC clinical program.

In data presented at ACG, investigators found a link between sex, lower BMI, and the development of irritable bowel syndrome in patients following a c. diff infection.

Isolation as a result of suspected C. Diff can take a significant financial toll on the healthcare system, thus it is necessary to determine appropriate factors that can predict CDI.

Relapses occurred in only 4 of 14 patients treated with the combination of Metronidazole with Vancomycin.

These findings suggest a potential in developing preventative vaccines against C. difficile infection.

New data shows that clinical isolates of C. difficile are variably affected by manuka honey in terms of growth inhibition and bactericidal activity.

Only 29.5% of sampled CBD users claimed any wellness benefit.

The absolute SCr criterion correlated better with all-cause mortality than the relative increase in serum creatinine.

New cohort analysis shows patients with ulcerative colitis or Crohn's disease who have received invasive care may be affected long-term.

These findings underline the importance of aggressive management to treat IBD and ACS comorbidities to improve outcomes.

This edition from the 10 Year Plan features perspective from leadership at WGO and Crohn's & Colitis Foundation, as well as survey results from gastroenterologists.

The trial was called off because of futility of the toxoid vaccine candidate.

The adjusted estimate of the burden of hospitalizations related to C. diff infections decreased by 24% between 2011-2017.

Low fecal intestinal secretory immunoglobin A is commonly found in infants of mothers in the antepartum and persistent depression trajectories.

A new study finds women and patients with a recent history of hospitalization were more likely to be colonized with C. difficile.

Miguel Regueiro, MD and George Khoudari, MD, both of the Cleveland Clinic, discuss predictors of colectomies for IBD-patients.

FMT was highly successful for the treatment of recurrent C difficile, and the cure rate was similar between groups who did and did not receive loperamide prior to the procedure.

Compared to hospitalized patients with ulcerative colitis but without C diff infection, hospitalized patients with ulcerative colitis and C diff experienced increased mortality.