Sickle Cell

A literature review identifies 3 broad factors that may contribute to bias in pain management of African Americans with SCD.

Few studies have specifically assessed the presentations and outcomes of sickle cell-related-leg ulcers in a female population.

A head-to-head assessment of the intravenous treatment options found greater efficacy for acetaminophen, supporting it more against the adverse effect-associated diclofenac.

Healthcare accessibility continues to be a significant barrier for patients and their families.

Number of red blood cell transfusions may be linked to decreased risk intrauterine fetal death.

The company suspended clinical trials of the gene therapy last month following patient diagnoses of acute myeloid leukemia and acute myelodysplastic syndrome.

Among 85 children with beta-thalassemia major and ≥5 years since primary vaccination, 23 were found to be seronegative.

Brain function improved with hydroxyurea treatment of sickle cell disease in prospective study with cerebrovascular and neuropsychologic measures.

A look back on key moments from Episode 1 of the Rare Disease Report podcast —featuring Kim Smith-Whitley, MD.

Although overall decrease in mortality was similar to the control group, sickle cell populations were still less likely to receive a kidney transplant.

In this first episode, Kim Smith-Whitley, MD, discusses the history, presentations, and research status of sickle cell disease.

Lisa Sarfaty, director of strategic planning for the National Organization for Rare Disorders, speaks on the role of the organization and the importance of the Rare Disease Day campaign.

Prevalence of anemia in patients with chronic kidney disease on hemodialysis found higher in Mexico than studied populations, with similar contributing factors.

Due to taboo or stigma, patients may not openly discuss their leg ulcers with their providers.

Up to 84% of younger patients note a positive experience with holistic therapeutic approaches to treating sickle cell-related pain.

An expert discusses findings that showed voxelotor (Oxbryta) improved leg ulcers in patients with sickle cell disease.

Vascular electrical stimulation therapy was associated with reduction in vaso-occlusive symptoms.

The suspension is due to recently reported diagnoses of AML and myelodysplastic syndrome in 2 treated patients.