
Opinion|Videos|May 16, 2025
Current Treatments Options for Patients With CHE
Author(s)Raj Chovatiya, MD, PhD
An expert discusses how chronic hand eczema (CHE) treatment follows a stepwise approach from general care and barrier protection to topical therapies (corticosteroids and calcineurin inhibitors) and systemic options (alitretinoin, immunosuppressives, and newer biologics for atopic dermatitis).
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Video content above is prompted by the following:
CHE Treatment Approaches
Key Themes:
- Treatment hierarchy: Baseline care (barrier protection, moisturization, and trigger avoidance), topical therapies, and systemic options.
- Topical treatments: Corticosteroids and calcineurin inhibitors show efficacy but have limitations for long-term use.
- Systemic options: Traditional immunosuppressants carry significant safety concerns, while newer targeted therapies for atopic dermatitis have been repurposed for CHE.
Notable Insights:
Dr Chovatiya discussed complications of long-term topical steroid use, including "skin thinning, loss of subcutaneous fat, potential systemic absorption, and even permanent depigmentation," emphasizing the need for better treatment options.
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