CHE: Symptoms and Diagnosis

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CHE Clinical Features and Diagnosis

Key Themes:

• Key clinical signs: Erythema, scaling, edema, vesicles, hyperkeratosis, fissures, and erosions, with more chronic than acute presentation.
• Differential diagnosis: Distinguishing CHE from atopic dermatitis requires a holistic history and full-body examination.
• Predominant symptoms: Beyond itching, skin pain represents a significant burden, particularly from fissures and cracking.

Notable Insights:

Dr Chovatiya emphasized that "from a patient perspective...a focus on skin pain as well as some of the cracking, bleeding, opening of skin, and wounding is going to be extraordinarily vital to really understanding the patient’s perspective."