Now Playing
Opinion|Videos|September 9, 2024
JAK Inhibitors and Pathophysiology of Atopic Dermatitis
After a brief introduction, medical experts review the pathophysiology of atopic dermatitis and explain how JAK inhibitors modulate this inflammatory condition.
Advertisement
Episodes in this series
Video content above is prompted by the following:
- Please provide a brief overview of the pathophysiology of atopic dermatitis (AD), a chronic inflammatory condition.
- How do JAK inhibitors contribute to the pathophysiology of AD?
Advertisement
Related to this article
KT-621, an oral STAT6 degrader, cut mean EASI by 62.6% after 4 weeks with no treatment-related adverse events in a phase 1b atopic dermatitis study.
Phase 2 and 3 data show difamilast 1% ointment improved severity and itch within 1 week in adults and children with mild to moderate atopic dermatitis.
Lindsay Ackerman, MD, and Chris Bunick, MD, PhD, examine how ORAL Surveillance shaped JAK warnings and what long-term atopic dermatitis data show.
In a phase 2 decentralized study, once-daily trientine tetrahydrochloride improved convenience and adherence in Wilson disease; 80% preferred it.
Type 2 biologics reduced mucus plugs in asthma trials, and quantitative imaging may help detect this treatable phenotype, according to a GOLD 2026 session.
In adults with late-onset PFIC, odevixibat improved pruritus within 3 months in a real-world study at presented at The Liver Meeting 2026.
CT-detected mucus plugs affect up to 67% of patients with COPD and are linked to worse lung function, exacerbations, and mortality, even without symptoms.
In patients with compensated MASH cirrhosis, Baveno VII and ANTICIPATE-NASH showed moderate agreement with HVPG and underestimated CSPH prevalence.
Advertisement
Advertisement
Trending on HCPLive
1
IDEAL: Seladelpar Achieves ALP Normalization in Second-Line PBC
2
Real-World Resmetirom Data Show Liver Stiffness Gains in MASH
3
ELSPIRE: Elafibranor Achieves ALP Normalization in 85% With PBC
4
Moving the Needle in Medicine: Mentorship, Teams, and Heart Failure Leadership, With Robert Mentz, MD
5