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Spotlight -

This Year In Medicine 2025

Opinion|Videos|September 16, 2024

Long-term Safety Data for JAK Inhibitors in Atopic Dermatitis

Author(s)Raj Chovatiya, MD, PhD, George Han, MD, PhD, Elizabeth Swanson, MD

Medical experts review phase 3 and long-term efficacy and safety data for abrocitinib and upadacitinib in atopic dermatitis and discuss how these data influence treatment decisions and any ongoing safety concerns.

Episodes in this series

EP. 1 JAK Inhibitors and Pathophysiology of Atopic Dermatitis

EP. 1 JAK Inhibitors and Pathophysiology of Atopic Dermatitis

EP. 2 Oral JAK inhibitors and Their Use for Treatment of Atopic Dermatitis

EP. 2 Oral JAK inhibitors and Their Use for Treatment of Atopic Dermatitis

EP. 3 Oral JAK Inhibitor Use in Atopic Dermatitis: Screening and Monitoring Patients

EP. 3 Oral JAK Inhibitor Use in Atopic Dermatitis: Screening and Monitoring Patients

EP. 4 Long-term Safety Data for JAK Inhibitors in Atopic Dermatitis

EP. 4 Long-term Safety Data for JAK Inhibitors in Atopic Dermatitis

EP. 5 Utilizing Long-Term Atopic Dermatitis Data in Clinical Practice

EP. 5 Utilizing Long-Term Atopic Dermatitis Data in Clinical Practice

EP. 6 Data on Early Itch Relief with JAK Inhibitors in Atopic Dermatitis

EP. 6 Data on Early Itch Relief with JAK Inhibitors in Atopic Dermatitis

EP. 7 Speed of Itch Relief in Atopic Dermatitis

EP. 7 Speed of Itch Relief in Atopic Dermatitis

EP. 8 Systemic Treatments and Switching Therapy in Atopic Dermatitis

EP. 8 Systemic Treatments and Switching Therapy in Atopic Dermatitis

EP. 9 Treatment Expectations and Patient Conversations in Atopic Dermatitis

EP. 9 Treatment Expectations and Patient Conversations in Atopic Dermatitis

EP. 10 Switching from Biologics to JAK Inhibitors in Atopic Dermatitis: Clinical Data

EP. 10 Switching from Biologics to JAK Inhibitors in Atopic Dermatitis: Clinical Data

EP. 11 Treatment Breaks and Rescue Treatments in Atopic Dermatitis

EP. 11 Treatment Breaks and Rescue Treatments in Atopic Dermatitis

EP. 12 Switching patients to JAK Inhibitors in Atopic Dermatitis in Clinical Practice

EP. 12 Switching patients to JAK Inhibitors in Atopic Dermatitis in Clinical Practice

EP. 13 Treatment Flexibility While on Abrocitinib in Atopic Dermatitis (JADE REGIMEN)

EP. 13 Treatment Flexibility While on Abrocitinib in Atopic Dermatitis (JADE REGIMEN)

EP. 14 Future Outlook for Atopic Dermatitis Treatments

EP. 14 Future Outlook for Atopic Dermatitis Treatments

Video content above is prompted by the following:

Please discuss phase 3 and long-term efficacy (International Global Assessment scores, Eczema Area and Severity Index scores, itch relief) and safety data for abrocitinib and upadacitinib in atopic dermatitis (AD).
How do the long-term data affect your decision to use oral JAK inhibitors in AD?
Do you have any safety concerns that have not been addressed by the long-term data so far?

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