
Opinion|Videos|December 12, 2025
Understanding the FDA-Approved TYK2 Inhibitor in Psoriasis
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Episodes in this series

Deucravacitinib, approved in 2022, was the first selective TYK2 inhibitor for moderate-to-severe psoriasis. Can you describe its mechanism of action?
What are your impressions of the recently published long-term data for deucravacitinib in plaque psoriasis, which demonstrated sustained efficacy and a consistent safety profile through five years of treatment?
How does this data influence your perception of its role in long-term disease management?
Which patients are ideal candidates for deucravacitinib?
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