Brandon May

Treatment regimens comprised of DCV+SOF±RBV and VEL/SOF+RBV offer similar cure rates among HCV patients with genotypes 2 and 3.

This observational data could serve an important role in pharmacoepidemiologic studies that would assess the overall benefit and risks of modern HCV therapies, namely direct-acting antivirals.

Female sex, previous gastrointestinal, and non-gastrointestinal comorbidities are associated with C difficile infection in women with UTIs, study finds.

A face-to-face, case-specific education intervention improved the management practices among nurses who cared for hospitalized patients with C difficile infections.

Investigators found 16S rRNA gene qPCR to be more sensitive than culture for detecting C difficile on environmental surfaces.

Implementation of antimicrobial stewardship programs in outpatient dialysis centers reduce infections caused by multidrug-resistant organisms, including Clostridium difficile.

The results of a recent study indicate that combination DAA regimens that include sofosbuvir are effective for achieving SVR in patients with chronic hepatitis C virus and compensated liver cirrhosis.

Investigators found associations between ART and ISTI-based regimens and increased viral suppression rates across the United States.

A new survey found that Clostridium difficile infections have a substantial impact on the health-related quality of work, work life, and physical activity of those who are infected.

Ridinilazole caused less microbiota disruption, and investigators believe it may be superior to vancomycin for preventing Clostridium difficile infection recurrence.

The dual use of ribavirin and direct-acting antivirals during treatment for hepatitis C virus was found to independently predict decline in mental health-related quality-of-life.

Clinical trials consistently demonstrate that fecal microbiota treatment is an effective treatment strategy for recurrent CDI, yet standardization practices vary.

One phase 2 study showed that RBX2660, a microbiota-based drug comprised of human stool, was effective in 77.8% of patients.

A probiotic hygiene system resulted in a greater reduction of healthcare-associated infections and surface bacteria than chlorine-based cleansers, including a 66.6% reduction of C. difficile.

Fecal microbiota transplant and oral metronidazole are equally effective and tolerated for C. difficile treatment.

Researchers suggest a need exists for integration of hepatitis C treatment into all facets of addiction care for individuals who inject drugs.

Converting from brand-name levetiracetam to generic version does not greatly increase seizure frequency among patients with epilepsy.

Firstborn children with ≥2 younger siblings have a 1.71 times higher risk of developing ADHD compared to children without siblings.

Patients with a co-infection of Clostridium difficile and ulcerative colitis or Crohn’s disease have higher rates of in-hospital mortality and health care resource utilization.

A new analysis shows a combination of ombitasvir/paritaprevir, ribavirin, and dasabuvir is safe and effective among older patients with HCV and cirrhosis.

A University of Surrey research professor has developed a mathematical model based on earlier models, for monitoring HCV progression and treatment response.

An amphetamine salts mixture (SHP465) showed efficacy in improving problem solving and sustaining attention in ADHD adults.

This is the first US initiative in to address the potential role of screening and isolation of asymptomatic C. difficile carriers in an outbreak setting as an adjunct to standard infection prevention measures.

In patients with hematologic malignancy, the polymerase chain reaction or enzyme immunoassay testing modalities may not be accurate for C. difficile diagnosis.

Adolescents with ADHD were more likely to use marijuana and cigarettes at earlier ages, which increased their risk of continuing substance use into adulthood.

Prenatal exposure to polycyclic aromatic hydrocarbons, as well as lifelong poverty, increased ADHD symptoms in children.

Patients receiving long-term care more likely to test positive for VRE than toxigenic C. difficile.

Drug resistance is increasing among HIV-positive patients, driven partly by transmission of resistance to and by ARV-naïve patients.

Long-term care facility residents with advanced dementia have substantial dysbiosis of their gut microbiome which may be able to identify subjects at high risk of C. difficile colonization.

The study adds new data in the developing world for the aging HIV population, suggesting that long-term cART exposure and HIV duration have harmful effects.