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Cannabidiol Produces Dose-Dependent Seizure Control in Adults and Children

Highly-purified cannabidiol (CBD) marketed as Epidiolex can lower the chances of seizures in adults and children with epilepsy.

Flu Cases Near 30 Million in the US, CDC Reports

Though weekly activity has slowed, experts insist the national activity remains high overall.

Spouses Who Live in Different States Face State Income-Tax Problems

Do you know the difference between a domicile and a residence? If you and your spouse are living apart understanding the difference will help you avoid unnecessary taxes.

Who Decides How Much Is Too Much?

Rapid Triage Testing Could Improve Outcomes for Patients with Acute Kidney Injury

David Ludvigson and Nam Tran, PhD, write about the need for rapid triage testing as a method of improving outcomes for patients with acute kidney injury.

ACAAI 2011: Guidelines for the Diagnosis and Management of Sinusitis/ Rhinosinusitis, Part 1

During his lecture, Dr. Eli O. Meltzer walked his audience through diagnosis and management guidelines of sinusitis/ rhinosinusitis at the ACAAI annual meeting.

Antithrombotic treatment of high-risk elderly patients hospitalized with atrial fibrillation

We assessed the pattern of use and the effectiveness of antithrombotic therapy in a cohort of high-risk elderly patients hospitalized for atrial fibrillation, with data derived from prescription, hospitalization, and mortality databases from 3 linked registries. Results showed that antithrombotic therapy was underused, even in patients with no comorbid conditions. In addition, patients exposed to antithrombotic therapy had a significantly lower mortality rate. The collection of epidemiological data by record linkage represents a flexible and readily available tool for monitoring and improving routine clinical care.

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Intracranial hemorrhage in atrial fibrillation: Is there a racial/ethnic difference?

We evaluated a multiethnic cohort of subjects with nonrheumatic atrial fibrillation hospitalized over a 6-year period to determine the racial and ethnic differences in the risk of intracranial hemorrhage (ICH) and the effect of warfarin treatment on ICH risk. Treatment with warfarin was associated with a 2-fold greater risk of ICH in whites, a 4- to 5-fold greater risk in both blacks and Hispanics, and a 15-fold greater risk in Asians. After adjusting for established stroke risk factors and warfarin use, Asians were 4 times as likely as whites to have ICH, whereas blacks and Hispanics were twice as likely.

Asystole during sleep in a 46-year-old male athlete

A number of electrocardiographic abnormalities have been described in athletes.1 Among these are sinus bradycardia and varying degrees of atrioventricular (AV) block. These findings have been attributed to the "athlete's heart," and are felt to be due to enhanced vagal tone seen with excellent physical conditioning. Secondarily it has also been suggested that there are intrinsic changes within the sinoatrial and AV nodes themselves, including prolonged sinus node recovery time and AV nodal Wenckebach, and these abnormalities persist following autonomic blockade.

ICD implantation: Knowing when to hold'em

We have seen a dramatic increase in use of ICDs along with expanded indications for these devices.

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How do cardiac and noncardiac conditions affect survival after ICD implantation?

The benefits of implantable cardioverter-defibrillators (ICDs) have been shown in randomized clinical trials. The factors that affect the risk–benefit ratio in a community setting, however, have not been evaluated.