Geriatrics

Researchers test 3 different machine learning models to aid in expanding the number of variables needed to better predict outcomes.

Genetically-indexed inhibition of TNF-TNFR1 signaling was predicted to reduce the risk of Crohn’s disease and ulcerative colitis, and increased the risk of multiple sclerosis.

Patients ≥65 years using glargine or detemir, rather than NPH insulin, had lower risk of hospitalizations or emergency department visits due to hypoglycemia.

Researchers see differences in how SARS-CoV-2 attacks the brain in comparison to the influenza virus that caused the 1918 pandemic.

The FDA recently issued the third EUA for a COVID-19 vaccine in the US.

All patients in the study who tested positive for COVID-19 suffered from mild or moderate symptoms.

Nonanastomotic biliary strictures occurred in 6% of the patients in the machine-perfusion group, while the complication occurred in 18% of the control group.

The Ad26 platform has been used in vaccines administered to nearly 200,000 real-world and clinical trial participants

Mediterranean region imposes partial lockdown following a surge in cases.

Alector’s announcement about the INVOKE-2 study follows a similar update regarding its INFRONT-3 study for frontotemporal dementia.

Approximately 13.8 million doses of COVID-19 vaccines have been administered during a 1 month period.

Compared with US census data, White individuals and women are overrepresented in clinical trials.

Noncompliance among younger patients and lack of education are issues that should continually be addressed by care teams.

Women were more likely than men to get the influenza vaccine, but less likely to receive the high-dose version.

Researchers find a significant benefit at day 28 when compared to a group taking a placebo.

Partnerships between primary care physicians and pulmonologists may improve vaccination rates for patients with COPD.

The number of individuals suffering from vision impairment expected to rise to 895 million by 2050.

The approval was based on data from the PARAGON-HF study.

More than 25% of adults in the US older than 65 have diabetes.

The Cassava Sciences agent showed 6-month improvements in both ADAS-Cog and NPI scores, and a phase 3 trial is expected to begin in late 2021.

Hydroxyurea therapy was associated with decreased rates of retinal thinning and could be a protective factor.

Participants who received the vaccine intranasally or through the tonsillar swab had significantly higher H5-specific neutralizing antibody levels than the group that received the vaccine orally.

A higher percentage of patients suffering from a severe mental disorder such as schizophrenia or bipolar disorder, died from a COVID-19 infection than the control group.

More than 20% of TIA patients suffered a stroke within 7 days following the baseline attack.

Low and moderate dosing shows the most potential in preventing AMD for patients with diabetes.