Geriatrics

New analyses suggest insomnia symptoms among older patients may play a pivotal role in the relationship between objective and self-reported cognition.

Research suggests disparities between racial and ethnic groups exist among patients with Alzheimer’s disease and related dementias.

Greater psychological resilience was associated with lower BMI, fewer hospitalizations, and greater mental QOL in the T2D population.

A recent study found that worsened visual acuity and depression were associated with neurobiological changes visible through MRI scans.

Vedolizumab was linked to an increased risk of treatment failure compared to TNF antagonists.

Research has highlighted new information for the identification of risk factors for dementia.

A study in China found that Parkinson’s patients treated with acupuncture saw reduced anxiety levels.

Despite worldwide trend data, incidence trends for dermatomyositis do not show increases among the study population.

A recent study in China aligns with findings regarding lower life quality rankings for older adults.

The phase 3 trial met its primary endpoint of mean rate of growth in GA area at 12 months with statistical significance and a favorable safety profile.

Rebecca T. Brown, MD, MPH, describes contributing factors to older homeless adult mortality and future topics of interest in this field.

The investigators identified 4 distinct subgroups—earlier rising/robust, shorter active period/less modelable, shorter active period/very weak, and later settling/very weak.

Patients with Parkinson disease had more pronounced sleep instability than those with other disorders marked by alpha-synuclein buildup, but those differences diminished after adjusting for medication differences, a new study found.

An Oakland-based analysis of mortality among homeless adults aged ≥50 years old illuminates the need for more proactive homeless care policies.

A recent study developed framework to improve fall prevention methodology across the country’s primary health care system.

Dr. Shear talked about the similarities and differences between depression and grief and the importance of recognizing both.

In the study, 2.10% of patients with Crohn’s disease and 1.90% of patients with ulcerative colitis were diagnosed with colorectal cancer.

The highest adjusted probability of CGM use occurred in middle adulthood, while the probability of CGM utilization decreased with increasing age in older adulthood.

The worldwide burden of vision loss continues to climb, but there may be solutions with regards to better access to care and improved screening.

The NDA was granted Priority Review designation with a PDUFA target action date of November 26, 2022.

Preventable factors including obesity, hypertension, and physical activity are disparately impacting the rate of dementia among people of color.

The numbers show a decrease in endophthalmitis cases after cataract surgery and an increase in endophthalmitis after intravitreal injection.

Non-vegetable nitrate intake was not associated with less frequent incident open-angle glaucoma.

There were also significant social determinants including race and religion discordance between the healthcare provider and patient and caregiver responsibilities toward others.

The HTRA1 and CFH risk alleles, family history of AMD, the LOC387715 risk allele, and cardiovascular disease were all linked to an increased risk of AMD.

The study authors suggest a thinner macular RNFL may predict a decline in cognitive performance.

Brent Forester, MD, MSc, discusses the confluence of biomarker and disease-targeting therapy in Alzheimer's, and the need to appropriately introduce these tools.

Dementia and Alzheimer's disease cases are anticipated to boom in coming decades. One expert stressed the need for improved screening and facilitation of care at the earliest stages and signs.

It takes even more than a village to provide the comprehensive care needed for aging, neurocognitive patients, says Rajesh R. Tampi, MD, MS.

Rajesh R. Tampi, MD, MS, discusses the evolved definition of dementia as a cognitive disorder, and how its spectrum of symptoms impact clinical development.