Geriatrics

After decades of unmet needs in the progressive form of vision loss, the complement inhibitor drug class is nearing the market for affected patients.

Data show older men and women are getting less and less sleep. However, women are much more likely to report such issues than men, despite faring slightly better in polysomnography tests.

The result show the gain in best-corrected visual acuity and the reduction in central subfield thickness at the conclusion of the core study was maintained up to week 24 of the extension study, with no differences in the safety profile.

The mean PCDP was estimated by 2 different methods to be 10.7 years and 10.1 years for open-angle glaucoma.

A faster rate of visual field progression was observed among 37 glaucomatous eyes treated with anti-VEGF for nAMD compared with a control group of 4304 eyes without anti-VEGF.

Individuals who were socially isolated at time of fracture had significantly worse function, ability to participate in social roles, and depression time of fracture.

In this study, the investigators assessed risk factors in patients with DRESS syndrome receiving vancomycin to treat gram-positive infections.

Genetic factors previously known to predispose people to hyperopia were not risk factors for clinically significant depression in the study.

New analyses suggest insomnia symptoms among older patients may play a pivotal role in the relationship between objective and self-reported cognition.

Research suggests disparities between racial and ethnic groups exist among patients with Alzheimer’s disease and related dementias.

Greater psychological resilience was associated with lower BMI, fewer hospitalizations, and greater mental QOL in the T2D population.

A recent study found that worsened visual acuity and depression were associated with neurobiological changes visible through MRI scans.

Vedolizumab was linked to an increased risk of treatment failure compared to TNF antagonists.

Research has highlighted new information for the identification of risk factors for dementia.

A study in China found that Parkinson’s patients treated with acupuncture saw reduced anxiety levels.

Despite worldwide trend data, incidence trends for dermatomyositis do not show increases among the study population.

A recent study in China aligns with findings regarding lower life quality rankings for older adults.

The phase 3 trial met its primary endpoint of mean rate of growth in GA area at 12 months with statistical significance and a favorable safety profile.

The investigators identified 4 distinct subgroups—earlier rising/robust, shorter active period/less modelable, shorter active period/very weak, and later settling/very weak.

Patients with Parkinson disease had more pronounced sleep instability than those with other disorders marked by alpha-synuclein buildup, but those differences diminished after adjusting for medication differences, a new study found.

An Oakland-based analysis of mortality among homeless adults aged ≥50 years old illuminates the need for more proactive homeless care policies.

A recent study developed framework to improve fall prevention methodology across the country’s primary health care system.

In the study, 2.10% of patients with Crohn’s disease and 1.90% of patients with ulcerative colitis were diagnosed with colorectal cancer.

The highest adjusted probability of CGM use occurred in middle adulthood, while the probability of CGM utilization decreased with increasing age in older adulthood.

The worldwide burden of vision loss continues to climb, but there may be solutions with regards to better access to care and improved screening.

The NDA was granted Priority Review designation with a PDUFA target action date of November 26, 2022.

Preventable factors including obesity, hypertension, and physical activity are disparately impacting the rate of dementia among people of color.

The numbers show a decrease in endophthalmitis cases after cataract surgery and an increase in endophthalmitis after intravitreal injection.

Non-vegetable nitrate intake was not associated with less frequent incident open-angle glaucoma.

There were also significant social determinants including race and religion discordance between the healthcare provider and patient and caregiver responsibilities toward others.