Major Depressive Disorder

Data show zolpidem use in 8-week insomnia trial reduced suicidal ideation in patients, even after trial randomization ended.

New data show high rate of depressive symptoms in patients with NTFE schizophrenia.

New data show adverse childhood experiences can cause personality changes proximal to trauma, rather than developing later in life.

Data show effectiveness of DSRM in treating major depressive disorder with less frequent discontinuations.

Late life depression is a known risk factor for dementia, impacting 8-16% in the US.

New data show mental health workers experienced lower levels of traumatic stress and peritraumatic distress during COVID-19 pandemic, compared to healthcare workers and general population.

New data show significant therapeutic effects of dextraomethadone treatment in MDD patients below the median percentage of life-years from diagnosis.

A new study from APA 2021 finds algorithm use can reduce clinical misdiagnosis of bipolar disorder as other mood disorders, including major depressive disorder.

New cross-sectional survey data suggest quality-of-life and psychological outcomes may differ in the most common chronic skin disease patient populations.

Dr. Jennifer Payne discusses how the events of the last year has impacted her patients and what needs to happen to improve mental health care in the future.

The odds of suicidal behavior was 49% lower for OUD patients receiving substance use disorder treatment.

Larger and longer clinical trials are needed to further test the treatment as a suitable option to treat depression.

A recent study finds no substantial increase in risk of suicide in the first months of COVID-19, particularly in high-income countries.

The study represents the first to examine a PPD connection to allopregnanolone.

Contrast suppression was substantially lower for patients with major depressive disorder.

Adults between 18-29 see the largest increase in mental health issues during the pandemic.

Sessions show promise helping alleviate stress and concern for COVID-19.

The once-daily, 14-day, oral therapy is being investigated for fast-acting clinical response in patients with major depressive disorder or postpartum depression.

BBT was compared to assisted referral to community outpatient mental health care.

Headache was the most prominent link between COVID-19 and depression.

The US has an underreported and perpetuating issue with clinician burnout and suicidality. Frontline caregivers consider what 1 year of a pandemic may have done to worsen it.

Sleep has increased since the beginning of the pandemic in college students, while social activity has decreased.

The study underscores the importance of interpreting patient-reported disease severity scores in the context of mental health factors.

Researchers find an increased risk of offspring ADHD symptoms due to maternal anxiety.

National survey data suggest that, well before COVID-19, the largest healthcare workforce in the US has been challenged by understaffing and stressful situations.