Major Depressive Disorder

A proof-of-concept trial shows a program that addresses sleep pressure, circadian rhythm and hyperarousal in adolescents and young adults receiving mental health care is promising.

New cohort analysis shows residents entering medicine in 2020 were actually less likely to report symptoms of PTSD than their earlier peers.

The pioneer in social anxiety disorder discusses his involvement in a promising, fast-acting nasal spray showing promising outcomes in late-stage trials.

Instances of urgent IBD hospitalization, surgery, death or lack of response to steroid therapy are linked to symptoms of depression and anxiety.

Vistagen reported significant improvement of physician- and patient-reported anxiety among trial participants who underwent an anxiety-inducing public speaking exercise.

Clayton, a primary investigator in the drug's pivotal trials, discusses what the historic FDA approval means for managing PPD in women.

The approval marks the first indication for a postpartum depression drug—one that which has been touted for its rapid-acting effect and sustained benefits.

The results found those with sexual minority status were significantly more likely to attend prenatal care visits (20%) when compared with heterosexual women.

While tele-CBT did not lead to significant changes in short-term weight outcomes, it was effective in improving disordered eating behaviors and reducing psychological distress.

"Depression causes a large public health burden, and alcohol-related behavior is a potentially modifiable risk factor," Dr. Gemma Hammerton writes.

The baseline data for the initial 1000 participants recruited into the TX-YDSRN show 79.6% were diagnosed with a primary depressive disorder.

Investigators discuss the potential of psychedelic drugs as a new approach to treating mental illnesses, highlighting their therapeutic benefits and the need for further research to understand their effects, safety, and accessibility.

During the early pandemic period, video telehealth use increased among all veteran groups but differences were observed among American Indian/Alaska Native veterans.

The study suggests 1 in every 18 patients would need an MRI scan to detect such significant abnormalities.

Structural discrimination, such as sexism and racism, can exacerbate mental health challenges, leading to higher suicidal thoughts and behavior rates among multiple marginalized individuals.

Because early detection of PPD is crucial and its prevalence is growing in the US, the condition poses significant risks to both maternal and neonatal health.

Data corresponding with DSM-IV symptoms were gathered around ages 18, 21, and 23 years and the primary outcome was depression at age 24.

Investigators noted both direct and indirect standardization are valid methods for comparing mortality rates. However, direct standardization is particularly useful when assessing disease burdens across multiple groups.

The findings underscore the importance of considering both the severity of BPD features and changes in depressive symptoms when assessing risk of suicide.

The study provides valuable insights into the medication behavior of patients receiving SSRIs.

"These findings may be used to change attitudes toward mental health disorders, promote greater mental health literacy, and promote policies to support needed services," investigators write.

The study revealed several concerning trends in the utilization of acute mental health care among youth during the second year of the COVID-19 pandemic.

England saw a significant increase in severe psychological distress among adults over the past 3 years, highlighting the urgent need to address the growing mental health crisis and allocate sufficient resources to mental health services.

Investigators systematically review data to further understand the relationship between sleep and PTSD as it impacts treatment outcomes.

A systematic review and meta-analysis of 10 studies observed that visual impairment significantly increased the risk of suicidal ideation, suicide attempt, and suicide death.

The prospective cohort study evaluates the role of both subjective and objective experiences.

From a novel acne cream to a breakthrough depression drug, a half-dozen agent decisions are coming through in the coming 6 months.

Telehealth likely will have a major place in psychiatric care in the future.

For participants reporting past-year suicidal experiences, there was decreased odds of attributing their suicidal experiences to the pandemic for veterans compared to nonveterans.

The investigators found an adjusted odds ratio of 1.74 for hospitalized suicide attempts and 1.45 for those who committed suicide in individuals with recent psychiatric history.