Ophthalmology

New trial results suggest the overall DONFL score was similar between a temporal inverted ILM flap technique and conventional ILM peeling in macular hole surgery.

Three-year results from the CIRTED trial reported no clear evidence of benefit for the addition of azathioprine to high dose oral steroid in individuals with moderate to severe TED.

An entire population gradually loses their vision, impeding everyday activities like driving in the dark, while investigators explore gene therapies in a race against the clock.

Smokers with TED showed less improvement in diplopia, proptosis, and overall clinical activity score compared to non-smokers.

The second pivotal Phase 3 trial reported NOV03 consistently met primary endpoints for signs and symptoms of DED associated with meibomian gland dysfunction.

A systematic review and meta-analysis of 27 studies reveal the prevalence of DR in pediatric T2D increased significantly more than 5 years after diagnosis.

Perfluorohexyloctane eye drops demonstrated significantly superior improvements in tCFS and eye dryness scores at day 57 compared with saline.

An economic analysis suggests Medicare reimbursement for complex cataract surgery fails to cover increased costs required for the procedure and may affect practice patterns.

A new study supports an individualized treatment plan for aflibercept, showing its improved efficacy with fewer injections over 2 years.

Eyes with DRIL were associated with more visual function loss and retinal blood circulation alterations compared to those with subfoveal ellipsoid zone loss only.

Baseline SRF was associated with rapid resolution of macular edema in both DME and RVO, but improvement in visual acuity was associated with SRF only in DME.

Nonacceptance of statin therapy was prevalent among women and could contribute to known sex disparities in the treatment of high cholesterol.

Most trial participants were identified as White and from high-income countries, stressing the need for action from the research community to increase representativeness.

A new analysis suggests the prevalence of myopia among children decreased and mean SER returned to the pre-pandemic levels after the lift of home confinement in China.

Findings from a recent study indicate a correlation between actual values of visual function and estimated values with a deep learning model using ultra-widefield FAF images.

The FDA assigned a PDUFA date of September 28, 2023 for the phentolamine ophthalmic solution 0.75%.

A 0.18-mg implant may be an effective option in managing noninfectious uveitis affecting the posterior segment.

Baseline evidence of deep capillary nonperfusion in eyes with clinically referable NPDR may predict short-term complications with high accuracy.

Investigators stress the need for timely surgical intervention to ensure favorable visual outcomes in patients with severe complications, including retinal detachment and vitreous hemorrhage.

Investigators from the University of Pennsylvania suggest the associations, particularly beta peripapillary atrophy, and tilted optic discs, should be accounted for when investigating glaucoma in high-risk black populations.

Age less than 3 months at surgery was associated with an elevated risk of glaucoma-related adverse events in aphakic eyes, but children with pseudophakia were less likely to develop a glaucoma-related adverse event.

An analysis of the China Stroke Primary Prevention Trial revealed the correlation was more notable when stratified by triglycerides levels and smoking status.

A nationwide study from the United Kingdom identified a low overall prevalence of stress-induced burnout by cataract surgery but reported a reduction in the feelings of personal achievement and a significant proportion willing to give up surgical responsibilities.

An analysis of the NIH All of Us Research Program suggests patients with glaucoma did not fare worse during the early stages of the COVID-19 pandemic, but still endured stress, social isolation, and probable depression.

Results of the LAMP2 trial indicate a delay of myopia onset and progression, rather than prevention, with 0.05% atropine eyedrop use, leading study investigators to call for further research.