Psychiatry

David Walling, PhD, discussed the results from a pharmacokinetic and safety study that evaluated aripiprazole lauroxil NanoCrystal Dispersion therapy initiation.

The technology includes enhanced features like a patient management system that increases the ease of use for physicians.

The 14-point guideline included recommendations for initial psychiatric evaluation and assessment, treatment goals and plans, use of multiple medications, and for patients that are pregnant or breastfeeding.

MDD and PTSD are significantly associated with military trauma and PTSD specifically, is at an increased with military sexual trauma among females.

The use of the popular smartphone application Pokémon GO—and possibly similar games—could have potential therapeutic benefits for those with mental illness.

According to survey data released by the American Psychiatric Association, almost 50% of Americans believe the crisis is impacting their peers, and 31% know someone addicted to opioids.

If approved, therapy would be the first of its kind to target Glx for the treatment of bipolar depression.

The mean level of anxiety has increased 5 points since 2017 on a 100-point scale, with Baby Boomers reporting a 7-point jump over the last year.

An analysis of 350,000-plus veterans found those who suffered concussions have at least a 2.51-fold increased risk of developing dementia.

Women who continued using antipsychotic medications during pregnancy had an absolute risk of 4.2% to 12% of developing gestational diabetes.

History of psychiatric disorder, especially in fathers and brothers, is highly valuable information to identify women most at risk for postpartum psychiatric illness.

Patients that had their medication selection guided by the GeneSight pharmacogenomic testing were 50% more likely to achieve remission and 30% more likely to achieve treatment response.

Patients with cannabis and cocaine use disorder have different impulsivity profiles, especially with relation to differences in attentional impulsiveness.

Results demonstrate potential to address a significant unmet for more than 30% of those suffering from treatment-resistant depression.

John Greden, MD, discussed the challenges physicians face in diagnosing, identifying, and treating depression, and the populations that are still severely underserved.

Darrell Kirch, MD, spoke at the APA’s annual meeting about the impact physician burnout has had and what can be done to address it and to improve clinician well-being.

Mayumi Okuda, MD, talked about what clinicians need to be doing and aware of in the identification of patients experiencing intimate partner violence.

Firearm use in the not guilty by reason of insanity population is more closely related to substance use and personality disorder than psychotic or mood disorders.

The associated PTSD comorbidities represent a significant public health problem that’s concomitant with increased disease burden and mortality.

The use of electroconvulsive therapy in patients with bipolar depression resulted in higher remission rates while showing similar response rates to unipolar major depression.

The algorithm is intended to help prevent mistakes caused by a slew of issues, from burnout at the end of a long day to overconfidence in decision-making.

This week on MDNN: Autism Spectrum Disorder rates are rising in the US, handwashing is effective for C. diff prevention, and PROMISE 1 trial results have been reported.

All told, 68% of the group receiving a full dose of MDMA no longer qualified for a PTSD diagnosis compared to 29% in the active-placebo control group.

The Global Head of Neurodegeneration for Genentech talks about the progress of 2 promising monoclonal antibodies.

The agency warns that the seizure and bipolar disorder medication can cause hemophagocytic lymphohistiocytosis, a rare but very serious immune system reaction.