News

Low eGFRcr-cys was more strongly and uniformly associated with adverse outcomes compared to low eGFRcr in an older patient population, highlighting the benefit of including cystatin C in GFR estimation.

Across two large, diverse cohorts, TET2 CHIP was associated with a more than 2-fold higher risk of incident HF with preserved ejection fraction.

In an interview, Andrew Blauvelt, MD, MBA, provides further perspective on the approval of roflumilast topical foam, 0.3% (Zoryve) and full publication of phase 3 STRATUM data.

A recent statewide analysis in California found TAVR rates exceed SAVR for severe aortic stenosis, despite contradicting consensus guideline recommendations.

VX-548 demonstrated a more rapid onset to meaningful pain relief post-surgery compared with placebo.

Study with 150,000 adults reveals 10% or more of unintentional weight loss associated with an elevated rate of cancer diagnosis within the next 12 months.

Regarding elective surgery, more than half of older adults in a survey study expressed concerns about pain and discomfort, as well as difficulty in recovery. Common concerns included costs, COVID-19 exposure, and time needed to be off work.

Vitiligo was significantly associated with an increased risk of bacteremia, cellulitis, and herpes zoster and was more common among those with female sex, Black compared to White race, Hispanic ethnicity, hepatitis C infection, and tobacco use.

This cardiology case report from Brady Pregerson, MD, features a woman in her 50s presenting with 3 days of body swelling and dyspnea. Check out the EKG and see if you can determine the correct diagnosis!

Although there was a greater prevalence of ALD and MetALD among male study participants, females had a greater risk of mortality from both SLD phenotypes, highlighting a potentially greater impact of alcohol consumption on women with liver disease than men.

A real-world analysis in the United States suggests hospital volume may not be the lone predictor of outcomes in pediatric cardiac surgery.

In recognition of 60 years since the historic contribution to modern understanding of the harmful effects of cigarette smoking, Albert Rizzo, MD, meets with the preventive cardiology expert to discuss the myriad of cascading effects delivered by the 1964 report.

In a 10-year follow-up study with over 1 million patients, multi-arterial grafting demonstrated superior long-term survival compared to single arterial grafting.

This new research may require additional follow up studies on potential harms, as 63% of those in this study’s electronic cigarette arm continue to use the product at 6 months.

A new survey study of high schoolers found alcohol, cannabis, and nicotine were linked to significant, moderate dose-dependent associations with worse symptoms of depression, anxiety, ADHD, general mental health, as well as suicidal thoughts.

Compared to glucagon-like peptide 1 receptor agonists and dipeptidyl peptidase 4 inhibitors, Use of sodium-glucose cotransporter 2 inhibitors was linked to a decreased risk of nephrolithiasis in patients with type 2 diabetes.

A systematic review of over 400 studies in type 2 diabetes reveals 13 biomarkers, including NT-proBNP and troponin-t, with potential to significantly enhance cardiovascular disease risk prediction.

In this segment of Lungcast, guest Sue Padernacht went further into the topic of mental health and burnout among clinicians, highlighting some ways to address the situation.

A new study found the periodic limb movement index, but not the apnea-hypopnea index, was linked to an increased risk of incident cardiovascular disease or death every 10 events per hour.

Results showed treatment with dapagliflozin 10 mg was associated with clinically meaningful attenuations in eGFR slope in patients with CKD and urinary albumin-to-creatinine ratio < 200 mg/g.

These data represent a significant step toward finding a causal connection for drug-induced alopecia, though further controlled studies may be necessary to isolate certain variables.

A survey found low success rates for multiple sleep treatments, including light therapy, light restriction, and melatonin.

More than half of patients received return-IBD care via telehealth in the post-COVID period, and those with longer drive times were more likely to continue telehealth care.

Approximately 1 in 8 children and adolescents exhibited myopic maculopathy change over a 4-year period, with enlargement of the diffuse atrophy the most common progression pattern.

Current approaches to vision screening in the US may not sufficiently cater to children of all sociodemographic backgrounds.

This segment of Lungcast guest Sue Padernacht’s discussion involved the very real topic of burnout among clinicians, as well as defining the differences between stress and burnout.

A new COSMOS study demonstrated how multivitamins had reduced cognitive aging by 2 years in older adults.