Preventing Cirrhosis Progression: Gut-Liver Axis, Circulation, Inflammation

Author(s):

Pamela Kushner, MD, FAAFP ,Nancy Reau, MD

Arun B. Jesudian, MD, discusses strategies to prevent the progression of cirrhosis, which include targeting microbiome abnormalities to improve the gut-liver axis, enhancing circulatory function, treating the inflammatory state, and addressing portal hypertension.

EP: 1.Exploring the Impact of Hepatic Encephalopathy on Patients and Their Families

EP: 2.Educating Primary Care Clinicians on Outpatient HE Management and Ammonia Testing

EP: 3.HE Experts on Symptoms, Risk Factors, Diagnosis Challenges, and Severity Grading

EP: 4.Collaborating with Specialists: Primary Care Clinician’s Evolving Role in HE Management

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EP: 5.Preventing Cirrhosis Progression: Gut-Liver Axis, Circulation, Inflammation

EP: 6.Hepatic Encephalopathy: Exploring Alterations in Microbiota Caused by Liver Disease

EP: 7.Current Hepatic Encephalopathy Therapies Targeting Gut-Liver Axis Disturbance

EP: 8.AASLD Guidelines for Hepatic Encephalopathy: Rifaximin's Role and Safety

EP: 9.Overview of Outpatient Strategies for Optimizing Patient Outcomes in HE

EP: 10.Managing Adverse Effects in HE Treatment

EP: 11.Practical Tips for the Primary Care Clinician Treating HE

EP: 12.Refractory Encephalopathy, Multivitamins and Closing Thoughts

What strategies do we have to target key pathogenic events in prevention of progression of cirrhosis?
- targeting microbiome abnormalities, to improve gut-liver axis
- improving the disturbed circulatory function
- treating the inflammatory state
- targeting portal hypertension