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Spotlight -

This Year In Medicine 2025

Opinion|Videos|June 25, 2024

Preventing Cirrhosis Progression: Gut-Liver Axis, Circulation, Inflammation

Author(s)Pamela Kushner, MD, FAAFP , Nancy Reau, MD, Arun Jesudian, MD

Arun B. Jesudian, MD, discusses strategies to prevent the progression of cirrhosis, which include targeting microbiome abnormalities to improve the gut-liver axis, enhancing circulatory function, treating the inflammatory state, and addressing portal hypertension.

Episodes in this series

Video 1 - 4 KOLs are featured in, "Exploring the Impact of Hepatic Encephalopathy on Patients and Their Families "

EP. 1 Exploring the Impact of Hepatic Encephalopathy on Patients and Their Families

Video 2 - 4 KOLs are featured in, "Educating Primary Care Clinicians on Outpatient HE Management and Ammonia Testing"

EP. 2 Educating Primary Care Clinicians on Outpatient HE Management and Ammonia Testing

Video 3 - 4 KOLs are featured in, "HE Experts on Symptoms, Risk Factors, Diagnosis Challenges, and Severity Grading"

EP. 3 HE Experts on Symptoms, Risk Factors, Diagnosis Challenges, and Severity Grading

Video 3 - 4 KOLs are featured in, "Collaborating with Specialists: Primary Care Clinician’s Evolving Role in HE Management"

EP. 4 Collaborating with Specialists: Primary Care Clinician’s Evolving Role in HE Management

4 KOLs are featured in this series

EP. 5 Preventing Cirrhosis Progression: Gut-Liver Axis, Circulation, Inflammation

4 KOLs are featured in this series

EP. 6 Hepatic Encephalopathy: Exploring Alterations in Microbiota Caused by Liver Disease

4 KOLs are featured in this series

EP. 7 Current Hepatic Encephalopathy Therapies Targeting Gut-Liver Axis Disturbance

4 KOLs are featured in this series

EP. 8 AASLD Guidelines for Hepatic Encephalopathy: Rifaximin's Role and Safety

4 KOLs are featured in this series

EP. 9 Overview of Outpatient Strategies for Optimizing Patient Outcomes in HE

4 KOLs are featured in this series

EP. 10 Managing Adverse Effects in HE Treatment

4 KOLs are featured in this series

EP. 11 Practical Tips for the Primary Care Clinician Treating HE

4 KOLs are featured in this series

EP. 12 Refractory Encephalopathy, Multivitamins and Closing Thoughts

What strategies do we have to target key pathogenic events in prevention of progression of cirrhosis?
- targeting microbiome abnormalities, to improve gut-liver axis
- improving the disturbed circulatory function
- treating the inflammatory state
- targeting portal hypertension

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