Starting Biologic Treatment Early in CD

Opinion
Video

Sara Horst, MD, MPH, comments on early introduction of biologics in the treatment of CD, highlighting her approach to initiating conversations with patients about advanced therapy.

This is a video synopsis/summary of a panel discussion involving Marla Dubinsky, MD; David Rubin, MD; Miguel Regueiro, MD; Remo Panaccione, MD, FRCPC; and Sara Horst, MD, MPH.

In this discussion, the focus is on the importance of early intervention in treating Crohn's disease, emphasizing the need for timely initiation of advanced therapies. The speaker underscores the empathy and compassion felt towards patients who have endured prolonged suffering without experiencing well-being or health.

The conversation delves into the significance of treating Crohn's disease early, given its progressive nature. Data suggests that starting biologic therapies closer to the time of diagnosis is more effective than initiating them after 2 or 4 years, as the disease might have been silently progressing for an extended period before diagnosis.

The panel addresses the challenge of educating patients and colleagues about the urgency of starting advanced therapies as soon as possible. The difficulty lies in convincing individuals who have been living with the disease for several years to accept the necessity of immediate intervention.

The speaker emphasizes the need for disease control and frames the conversation around giving patients back a sense of control over their lives. The goal is to provide stability and prevent the waxing and waning of symptoms. The term "advanced therapies" is discussed, acknowledging its potential stigma and suggesting a shift towards focusing on effective treatment for Crohn's disease.

The discussion concludes with an emphasis on achieving long-term goals and protecting patients in the future by treating the disease early with the most effective agents. The speakers recognize the challenge of addressing this issue, especially with newly diagnosed patients who may find the concept overwhelming. Overall, the panel highlights the importance of early intervention and effective communication to ensure optimal outcomes for Crohn's disease patients.

Video synopsis is AI-generated and reviewed by HCPLive editorial staff.

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Marla Dubinsky, MD | Credit: LinkedIn
Marla Dubinsky, MD | Credit: LinkedIn
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