A. Bonnie Gillis


Novel Therapy First to Extend Survival in Advanced Melanoma

The results of a randomized phase III study showed that when ipilimumab (also known as MDX-010) was administered with or without the gp100 peptide vaccine, it extended survival by 34% compared with the gp100 peptide vaccine alone in patients with previously treated advanced melanoma.

J. Michael Boyd, PharmD


Dronedarone: Boon or bust?

Atrial fibrillation affects over 2.2 million Americans and is estimated to affect up to 10 million by 2050.

Sarah Nelson, McDermott Will & Emery, LLP


Proposed Physician Fee Schedule Update Implements Reform Provisions

CMS published its annual regulatory update to the Medicare Physician Fee Schedule, including rules implementing key provisions of the Affordable Care Act.

Chris Cole


Practice Management: Money Talks

News and online resources to help you make better financial decisions for your practice.

director of vascular


Patent foramen ovale closure for stroke prevention: A myriad of unanswered questions

Migraines, including those with aura, are common and generally benign, affecting between 10% and 15% of the population.

Courtney Sullivan, MS IV


Mediterranean Diet as a Primary Prevention of Cardiovascular Disease

Compared to a low-fat diet, adherence to a Mediterranean diet has significant benefit in the primary prevention of cardiovascular disease among patients aged 55-80 years old at high baseline cardiovascular risk without cardiovascular disease.

Scott Glaser, MD


Interventional Pain Management: Let's Abandon the Safe Triangle

Using the widely taught 'safe triangle' approach to transforaminal epidural injections can paralyze patients. There's a safer way.

Catherine M. Champagne, PhD, RD4: From the 1Center for Health Research, Kaiser Permanente Northwes


Comprehensive lifestyle modification and blood pressure control

Lifestyle recommendations for the prevention and treatment of hypertension include weight loss, reduced sodium intake, increased physical activity, limited alcohol intake, and the Dietary Approaches to Stop Hypertension (DASH) diet. The 18-month results of the Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER) randomized clinical trial showed that individuals with prehypertension and stage 1 hypertension can make and sustain many of these lifestyle changes over the long term, thereby reducing their risk of cardiovascular disease.

Tejus Pradeep, BA


Ergonomics May Be the Key to Longevity for Ophthalmologists

Poor posture in surgical care has been long associated with worsened clinician health. It is no different in ophthalmology.

Adam Sturts, MSIV


Telemedicine Tools Emerging in Medical School

Artificial intelligence has the potential to enhance many aspects of healthcare in the US, including patient and clinical outcomes, while reducing costs.

Keli Rising


Does Race Impact Mortality Rates in Patients with End-stage Renal Disease?

During a press conference at Kidney Week 2011, Sandra Amaral, MD, MHS, Children's Hospital of Philadelphia, stressed how important it is for pediatricians and pediatric nephrologists to promote the process of kidney transplant to happen as soon as possible in children who are diagnosed with ESRD.

Belinda Ostrowsky, MD, MPH


Let's Get Smart about Antibiotic Prescribing

Antibiotics are commonly prescribed by a wide range of clinicians. Data suggest that up to 50% of prescribed antibiotics are "unnecessary" or "inappropriate".

Riccardo Cappato, MD1


Integrating the existing emergency medical system with automated external defibrillators for out-of-hospital cardiac arrest

We investigated whether a program based on diffuse deployment of automated external defibrillators operated by trained volunteers and laypersons across the largest county in Italy would safely and effectively improve the current survival rate among patients with out-of-hospital cardiac arrest. Compared with historical control subjects, the new strategy resulted in a 3-fold increase in 1-year survival free of neurologic impairment.

Mart Fox, Yvonne


Who Can Sign Your Checks?

Whether you are incorporated or are sole proprietor, your spouse should be signatory to your business checking account.

Steven Abernathy


Estate Planning Essentials for Physicians

Planning can dramatically reduce-or avoid altogether-some common tax hits, including: capital gains, state, inheritance, and estate and gift taxes. There are several options to consider when building an estate plan.

Shannon W. Finks, PharmD, BCPS


Procainamide-induced Pleural and Pericardial Effusions

Drug-induced diseases and serious adverse drug effects can alter therapeutic plans and greatly affect patient outcomes. Many medications are known to have a narrow therapeutic index and to require close patient monitoring.

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