Atherosclerotic Cardiovascular Disease

A genome-wide genetic association study using mendelian randomization provides insight into the causal relationships between HDPs and coronary artery disease and ischemic stroke later in life.

An analysis of actigraphy data obtained from the MESA Sleep Ancillary Study indicates irregularities in sleep patterns, particularly in duration and timing of sleep, were linked to increased markers of subclinical atherosclerosis, including increased coronary artery calcium burden.

An analysis of the UK Biobank suggests individuals with celiac disease had an incidence rate of 9.0 CVD cases per 1000 person years compared with 7.4 per 1000 person years in people with no celiac disease.

The late-breaking findings suggest the potential prognostic benefit of highly purified EPA in patients with chronic CAD with a low EPA/AA ratio.

Announced on May 13, the Onyx Frontier DES carries the same clinical indications as Medtronic's Resolute Onyx DES and will be available in 2.0 mm sizes as well as 4.50-5.00 mm sizes that can be expanded to 6.00 mm.

Data from the DISCHARGE trial provides evidence demonstrating computed tomography could be a safe alternative to catheterization in patients with stable chest pain and suspected CAD.

An analysis of nearly 1000 patients from Spain is providing clinicians with insight into factors that could help predict negative outcomes among patients with stable coronary artery disease.

Deepak Bhatt, MD, MPH, provides perspective on the results of the REDUCE-IT PAD analysis he presented at the American Heart Association 2021 Scientific Sessions.

Arnold Meshkov, MD, explores how discoveries and the advent of new technologies have influenced diagnosis of atherosclerosis throughout history.

Leveraging data from 3 European cohorts, investigators detail the risk of incident coronary heart disease and mortality associated with iron deficiency in the general population.

An analysis of data from the COMPASS study suggests the addition of low-dose rivaroxaban to aspirin resulted in benefits, irrespective of concomitant therapies or comorbidities.

A cross-sectional analysis of data suggests more than 20% of patients with coronary artery disease report experiencing angina at least once a month while 12.5% report experiencing angina daily or weekly.

An analysis of data from 10k women in the Lifetime Risk Pooling Project presented at EPI Lifestyle 2021 suggests premature menopause was associated with a 40% increase in risk of coronary heart disease.

A new analysis of claims data performed by clinicians at Penn Medicine suggests less than 1% of patients with ASCVD initiated therapy with a PCKS9 inhibitor from 2015-2019.

Results of a 305-patient trial indicate ischemic leg pain could serve as a threshold for whether or not a patient with peripheral artery disease will see a meaningful improvement in walking score from their walking routine.

An analysis of more than 1.2 million patients from an STS database suggests women were 14-22% less likely to undergo guideline-recommended revascularization procedures than their male counterparts.

An analysis of data and blood samples from more than 28k women provides insight into the predictive value of more than 50 biomarkers for predicting risk of premature coronary heart disease in aging women.

A randomized trial provides further insight into the effects of intensive lifestyle interventions on coronary plaque progression in patients with nonobstructive coronary artery disease.

An analysis of data from 3 major studies details associations between diets characterized by intake of pro versus anti-inflammatory foods with incidence of cardiovascular disease.

A study from ESC Congress 2020 dove deeper into associations between specific biomarkers and risk of CV events in CAD patients with and without diabetes.

Full data from the EVAPORATE trial presented at ESC Congress 2020 add further evidence of the cardiovascular benefits from use of icosapent ethyl.

An analysis of data from a Society of Vascular Surgeons registry is shedding light on the use of DAPT in patients following peripheral vascular interventions.

A new study is detailing the increased risk of coronary artery disease associated with certain reproductive factors in postmenopausal women.

Among Hispanic and Latino patients with peripheral artery disease 31% reported use of antiplatelet therapy, 26% reported use of lipid-lowering therapy, and 57% reported use of antihypertensive therapy in a new study.

An analysis of 10 randomized clinical trials is shedding new light on the risk of MACE seen by Black patients following PCI versus risk among white counterparts.