Gastroenterology

Most patients who were treated with direct-acting antivirals for hepatitis C virus infection saw improvement in oral lichen planus symptoms, including 6 of 10 who saw complete remission.

Individuals with malnutrition had higher mortality rates, as well as higher rates of sepsis and pneumonia.

Investigators determined that acid-base disturbances like lactate clearance influenced C diff infection after cardiac surgery.

Overdiagnosis of the infection is driving drug resistance while cases increase. A team of experts consider the value of stewardship in refining care.

A small study found oral vancomycin prophylaxis prevented C diff infection in thoracic transplant patients.

Interferon-based therapy is generable intolerable for the older population.

NAFLD can be common among those with diabetes or those who are obese.

Researchers comb through the data from more than 50,000 liver cirrhosis patients in Japan.

Patients in mature adulthood may have different risk factors for recurrent C diff infection than their elderly counterparts.

Researchers found 8 meta-analysis and systematic reviews showing the positive link between PPI use and the risk of clostridium difficile infections.

Approximately 50% of COVID-19 patients have some form of gastrointestinal symptoms.

Exposure to PPIs was associated with a moderate increase in the risk of community-acquired C diff infection, even after treatment discontinuation.

Albumin infusions did not result in statistically significant differences in predefined study endpoints.

More patients also achieved endoscopic and histologic remission in the treatment group compared to the placebo group.

How dupilumab is observed to benefit EoE patients—and who may administer the biologic therapy.

Perspective on how the interleukin-targeting biologic has unique benefit for the rare, under-resourced disease.

“A high or rising white blood cell count in isolation is not a sufficient indication for C diff infection testing,” the study authors said.

The findings should assuage concerns about small intestinal bacterial overgrowth when prescribing treatment with proton pump inhibitors.

Nonanastomotic biliary strictures occurred in 6% of the patients in the machine-perfusion group, while the complication occurred in 18% of the control group.

In the U-ACCOMPLISH study, 37% of patients treated with upadacitinib achieved histologic-endoscopic mucosal improvement at week 8.