Gastroenterology

Patients in mature adulthood may have different risk factors for recurrent C diff infection than their elderly counterparts.

Researchers found 8 meta-analysis and systematic reviews showing the positive link between PPI use and the risk of clostridium difficile infections.

Approximately 50% of COVID-19 patients have some form of gastrointestinal symptoms.

Exposure to PPIs was associated with a moderate increase in the risk of community-acquired C diff infection, even after treatment discontinuation.

Albumin infusions did not result in statistically significant differences in predefined study endpoints.

More patients also achieved endoscopic and histologic remission in the treatment group compared to the placebo group.

How dupilumab is observed to benefit EoE patients—and who may administer the biologic therapy.

Perspective on how the interleukin-targeting biologic has unique benefit for the rare, under-resourced disease.

“A high or rising white blood cell count in isolation is not a sufficient indication for C diff infection testing,” the study authors said.

The findings should assuage concerns about small intestinal bacterial overgrowth when prescribing treatment with proton pump inhibitors.

Nonanastomotic biliary strictures occurred in 6% of the patients in the machine-perfusion group, while the complication occurred in 18% of the control group.

In the U-ACCOMPLISH study, 37% of patients treated with upadacitinib achieved histologic-endoscopic mucosal improvement at week 8.

Linaclotide has been marketed as LINZESS to treat irritable bowel syndrome with constipation.

Crohn’s disease patients and ulcerative colitis patients showed changes in energetic metabolism in plasma and biopsy samples compared to a control group.

A cohort assessment shows a 57% increased risk of pediatric asthma development among children given PPIs to treat gastrointestinal tract disorders.

Women infected with either virus generally experienced higher incidences of premature births compared with healthy women.