The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
NUDGE-FLU Analysis Finds History of Heart Attack Increases Effectiveness of CV Gain Frame Letter
Electronic messages highlighting cardiovascular benefits of flu shots increased vaccination rates by 1.8% in heart attack survivors.
Emapalumab May Improve Response Rates in MAS Treatment
Findings from the first and only controlled study for macrophage activation syndrome were presented at the ACR Convergence.
Barry A. Borlaug, MD: Impact of Tirzepatide on Cardiorenal End-Organ Damage in HFpEF
Barry A. Borlaug, MD describes the beneficial effect of tirzepatide on circulatory pressure-volume overload and end-organ damage in patients with HFpEF and obesity.
Shreena K. Gandhi, MBBS: Recognizing Fibromyalgia as a Continuous Variable, Trait Diagnosis
Gandhi discussed examining social security disability rates and how SSD criteria may clash with a trait disease like fibromyalgia.
ITCH-E: Pruritus Linked to Worse Health-Related Quality of Life in PBC
Patients with PBC and moderate/severe pruritus face a greater health-related quality of life burden and impaired activity than those with no/mild itch.
Minjee Kim, MD: Understanding Sleep’s Impact on Post-Liver Transplant Outcomes
Kim explains how poor sleep is linked to negative impacts on mental health, physical health, and frailty after liver transplantation.
GLORIOUS: Exenatide Lacks Preventive Effect on Organ Injury in Cardiac Surgery
An IV infusion of exenatide during cardiac surgeries involving bypass did not significantly benefit mortality or organ injury compared with placebo.
Oussama Wazni, MD, MBA: OPTION Trial and the Role of LAAC in Atrial Fibrillation
Oussama Wazni, MD, discusses the results of the OPTION trial examining LAAC in atrial fibrillation as well as its reception as AHA 2024.
Obesity-Related Heart Disease Deaths Rose Roughly 180% Since 1999
Obesity-related ischemic heart disease deaths rose from 1999 to 2020, particularly in middle-aged men and Black adults, per CDC WONDER data.
Reducing Treatment Burden of Pegloticase for Uncontrolled Gout, with Orrin Troum, MD
Troum discussed positive efficacy and safety findings from the phase 4 AGILE study.
Exploring CAR T-cell Therapy for Rheumatic/Autoimmune Diseases With Georg Schett, MD
Schett discussed findings from 2 early studies of CD19 CAR T-cell therapy.
TCE Therapy Demonstrates Quick Responses for Systemic Lupus Erthematosus in Early Data
A-319 has been well-tolerated so far and dose-escalation is ongoing in the phase 1 trial.
Elafibranor Improves Predicted Transplant-Free Survival Based on GLOBE, UK-PBC Scores
Treatment with elafibranor (Iqirvo) improved prognostic GLOBE and UK-PBC scores as early as week 4 in the phase 3 ELATIVE trial.
Interim Phase 1 Update Shows Favorable Effect of Nex-z for ATTR-CM
A single dose of nex-z achieved consistent and rapid reductions in serum TTR levels over 12 months of follow-up in patients with ATTR-CM.
VANISH2: Catheter Ablation Viable First-Line Option for Ventricular Tachycardia
Initial catheter ablation achieved a lower risk of a composite primary endpoint event than anti-arrhythmic drug therapy in patients who survived a heart attack.
Chari Cohen, DrPH, MPH: Healthcare Providers’ Role in HBV Clinical Trial Diversity
Cohen explains patient perspectives about how healthcare providers can help address the lack of diversity in chronic HBV clinical trials.
Rapid Initiation of SGLT2 Inhibitors Improves Cost-Effectiveness of Therapy, with Ankeet Bhatt, MD, MBA
Ankeet Bhatt, MD, MBA, discusses a study he led from AHA 2024 examining the cost-effectiveness of dapagliflozin based on how soon therapy was initiated following diagnosis or hospitalization.
Hide Okuno, MS: Tube Weaning Reduces Parental Stress, Findings Guide Future Studies
At NASPGHAN 2024, Okuno shared findings on reduced parental stress after children’s tube weaning, emphasizing the potential for new outpatient weaning protocols.
Vitamin D Deficiency Linked to Worse Autoimmune Hepatitis Outcomes
Patients with autoimmune hepatitis who are deficient in vitamin D had worse outcomes than patients with normal vitamin D levels.
Jonathan Stine, MD: Exercise’s Benefit in MASH is Independent of Weight Loss
Stine reviews findings from a posthoc analysis of the NASHFit trial suggesting the impact of exercise on MASH resolution, even without weight loss.
Intensive Blood Pressure Regimen Lowers CVD Risk in People with T2D
Reducing systolic blood pressure to less than 120 mmHg lowered the risk of major cardiovascular events for most people with diabetes in the BPROAD trial.
SUMMIT Trial Proves Tirzepatide's Benefit in HFpEF with Obesity
Tirzepatide reduced the risk of heart failure hospitalization or cardiovascular death by 38% and improved body weight by up to 21% in the SUMMIT trial.
Telehealth Could Address HCV Care Barriers, Expand Treatment for People Who Inject Drugs
Zoi Papalamprakopoulou, MD, explains telehealth’s potential to aid HCV treatment in high-risk populations and how patients perceive this care modality.
John Stone, MD, MPH: Inebilizumab Efficacious for IgG4-Related Disease in MITIGATE Study
Stone discussed findings from the first randomized, double-blind, placebo-controlled trial for IgG4-related disease.
Glucocorticosteroid Use for Rheumatoid Arthritis Increases CVD, Infection Mortality Risk Even After Cessation
People who used GC for over 2 years and 3 years had elevated risks of CVD and infection-related mortality, respectively, that never returned to pre-GC use levels.
Study Highlights Real-World Characteristics of Providers Treating Psoriasis in US
In this cross-sectional survey analysis, new insights were explored regarding clinical practice patterns and treatment outcomes within dermatology practices in the US.
Wei Zhang, MD, PhD: Optimizing Post-Liver Transplant Care for High-Risk Patients
Zhang describes how a novel multidisciplinary care clinic has helped reduce relapse after transplant in patients with alcohol-associated liver disease.
Idorsia Launches Aprocitentan (TRYVIO) in US For Treatment of Hypertension
Once-daily aprocitentan is indicated to help lower blood pressure in adult patients with hypertension who are inadequately controlled on other medications.
IL-18 Levels Associated With Long COVID Risk in People With Rheumatic Diseases
IL-18 levels were consistently lower across participants with different SARDs, remission status, and COVID-19 disease characteristics.
VTP-300, Nivolumab Combination Shows Promise for Functional HBV Cure in Phase 2b Trial
New phase 2b data suggest a combination of VTP-300 and low-dose nivolumab can stimulate immune response and induce HBV functional cure.